৳ 17/unit
Pack: ৳ 170
৳ 17/unit
Pack: ৳ 170
At a glance
Methylphenidate Hydrochloride is a CNS stimulant used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.
Indications
- Attention Deficit Hyperactivity Disorder (ADHD)
- Narcolepsy
Pharmacology
Methylphenidate (MPH) acts as a norepinephrine and dopamine reuptake inhibitor (NDRI), increasing the presence of these neurotransmitters in the extraneuronal space and prolonging their action. At low doses, it selectively activates NE and DA neurotransmission within the prefrontal cortex.
Dosage
Adult Dose:
- Narcolepsy and ADHD: 20-30 mg/day (2-3 divided doses), 30-45 minutes before meals
- 10-15 mg/day may be adequate for some patients; 40-60 mg/day for others
- Last dose should be taken before 6 pm (to avoid sleep problems)
Child Dose (6 years and older):
- Initial: 5 mg 1-2 times daily (30-45 min before breakfast and lunch)
- May increase by 5-10 mg/day at weekly intervals
- Maximum: 60 mg/day (2-3 divided doses)
- Under 6 years: Safety and efficacy not established
Side effects
Common Side Effects:
- Headache
- Insomnia (difficulty sleeping)
- Abdominal pain
- Nervousness
- Restlessness
- Dizziness
Rare Side Effects:
- Tremor, convulsion
- Rash, pruritus, urticaria
- Fever, arthralgia
- Alopecia, exfoliative dermatitis
- Thrombocytopenic purpura
- Leukopenia
- Liver damage (very rare)
Use in pregnancy
Use in Pregnancy: Possibly unsafe. Limited human studies; animal studies show harmful effects on developing baby. Your doctor will weigh benefits and risks.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- High habit-forming potential - do not take more than prescribed
- Caution while driving (may cause dizziness, blurred vision)
- Monitor blood pressure and pulse
- Monitor height and weight in children regularly (may decrease appetite)
- Inform doctor if sudden mood changes or suicidal thoughts occur
- Do not stop without consulting your doctor
- Caution in mild hypertension; contraindicated in moderate/severe hypertension
Overdose effects
Acute overdose symptoms: nausea, vomiting, agitation, convulsions, delirium, hallucinations, sweating, flushing, headache, hyperthermia, tachycardia, palpitations, mydriasis, dry mouth, coma. Symptomatic treatment.
Storage conditions
Store below 25°C in a cool and dry place, away from light. Keep out of reach of children.