৳ 5/unit
Pack: ৳ 5
৳ 5/unit
Pack: ৳ 5
At a glance
Caffeine + Ergotamine Tartrate is a combination medicine used in the treatment of acute migraine attacks. Ergotamine constricts blood vessels in the head, and caffeine enhances its absorption, helping to relieve migraine pain.
Indications
- Migraine
- Vascular headache
Pharmacology
Ergotamine tartrate is an ergot alkaloid that acts directly on vascular smooth muscle to cause vasoconstriction. It constricts intracranial blood vessels that are dilated during migraine, thereby relieving pain. Caffeine is a methylxanthine that stimulates the central nervous system and enhances the absorption and bioavailability of ergotamine.
Dosage
Adults and children above 12 years:
Take 1-2 tablets at the first sign of a migraine attack.
If necessary, take 1-2 tablets every 30-60 minutes.
Maximum dose: No more than 4-6 tablets per day; no more than 8-10 tablets per week.
Note: Not for chronic daily use. Do not exceed the recommended dosage for migraine treatment.
Side effects
Common side effects: Nausea, vomiting, diarrhea, muscle pain, increased heart rate, restlessness.
Serious side effects: Numbness or tingling in fingers and toes, muscle pain in arms and legs, weakness in legs, chest pain, changes in heart rate, swelling or itching.
Long-term use: Retroperitoneal fibrosis, pleuropulmonary fibrosis, fibrotic thickening of heart valves (rare).
Signs of ergotism: Intense arterial vasoconstriction, peripheral vascular ischemia, numbness, coldness, pallor of digits (may lead to gangrene).
Use in pregnancy
Highly unsafe during pregnancy (Category X). Ergotamine can cause uterine contractions and fetal harm. Contraindicated in pregnant women.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not exceed recommended dosage; not for chronic daily use.
- Rebound headache may occur upon discontinuation (rare).
- Do not use during pregnancy and lactation.
- Caution in patients with liver and kidney disease.
- Avoid in peripheral vascular disease, coronary heart disease, hypertension, and sepsis.
Overdose effects
Overdose symptoms: Nausea, vomiting, abdominal pain, increased heart rate, dizziness, drowsiness, confusion, convulsions, unconsciousness. Consult your doctor immediately if overdose is suspected.
Storage conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.