Mycotil500mg
Rx- Generic:
- Mycophenolate Mofetil
- Company:
- EDCL
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 55/unit
Pack: ৳ 55
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- ৳ 55
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At a glance
Mycophenolate Mofetil is an immunosuppressant used to prevent organ rejection after transplantation. It suppresses the immune system by inhibiting lymphocyte proliferation.
Indications
- Prophylaxis of acute organ rejection in renal transplant
- Prophylaxis of acute organ rejection in cardiac transplant
- Prophylaxis of acute organ rejection in hepatic transplant
- Induction and maintenance therapy of Class III-V lupus nephritis
Dosage
Renal Transplant (Adult): 1 g twice daily (2 g daily dose)
Renal Transplant (Pediatric, 3 months-18 years): BSA 1.25-1.5 m²: 750 mg twice daily; BSA >1.5 m²: 1 g twice daily
Cardiac Transplant (Adult): 1.5 g twice daily (3 g daily dose)
Hepatic Transplant (Adult): 1.5 g twice daily (3 g daily dose)
Lupus Nephritis (Adult): Induction: 750 mg-1.5 g twice daily; Maintenance: 500 mg-1 g twice daily
Lupus Nephritis (Pediatric): Induction: 600 mg/m² twice daily (max 2 g/day); Maintenance: 300 mg/m² twice daily
Side effects
Common Side Effects (>10%):
- Diarrhea (21%)
- Leukopenia (34%)
- Nausea (23%)
- Vomiting
- Abdominal pain (27%)
- Sepsis
- Gastrointestinal candidiasis
- Urinary tract infection (34%)
- Hyperglycemia (44%)
- Hypertension (28%)
Serious: Opportunistic infections, lymphoma, skin cancers, GI bleeding
Precautions & warnings
- May increase new or reactive viral infections (hepatitis B/C, polyomaviruses)
- May cause blood dyscrasias (including pure red cell aplasia)
- May cause serious GI tract complications (bleeding, perforations, ulcers)
- May increase risk of lymphomas and other malignancies
- Avoid live vaccines
- Do not donate blood during therapy
- Use sunscreen to prevent skin cancer