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At a glance

Dopamine Hydrochloride is used for the treatment of low blood pressure due to heart attack, infection, heart surgery, or trauma. It increases blood pressure by increasing pumping capacity of the heart and improving blood flow, and may help prevent kidney failure in critically ill patients.

Indications
  • Heart failure
  • Low blood pressure
Pharmacology

Dopamine stimulates α, β and dopamine receptors. At lower doses it produces renal and mesenteric vasodilation, while at higher doses it stimulates cardiac stimulation and renal vasodilation.

Dosage

Adult Dose: Hemodynamic conditions: 1-5 mcg/kg/min IV (low dose), 5-15 mcg/kg/min (medium dose), 20-50 mcg/kg/min (high dose). Increase by 1-4 mcg/kg/min at 10-30 min intervals. Titrate to desired response.

Child Dose: 1-5 mcg/kg/min IV, increased to 5-20 mcg/kg/min; not to exceed 50 mcg/kg/min.

Side effects

Common Side Effects:

  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Headache
  • Increased heart rate
  • Palpitations
Use in pregnancy

Dopamine Hydrochloride may be unsafe during pregnancy. Animal studies have shown harmful effects. Doctor will weigh benefits and risks.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Intended for use in hospitalized patients.
  • Regular monitoring of heartbeat, blood pressure, urine output, liver and kidney function required.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Overdose effects

In case of accidental overdosage, reduce rate or temporarily discontinue. Use phentolamine if needed.

Storage conditions

Store below 25°C, away from light & moisture. Keep out of reach of children.

Dopamine Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.