Nacid

• Gastroesophageal Reflux Disease (Acid Reflux): Used for treatment of acid reflux.
• Peptic Ulcer Disease: Used for treatment of gastric and duodenal ulcers.
• Gastric Ulcer: Used for treatment of stomach ulcers.
• Zollinger-Ellison Syndrome: Used for treatment of excessive acid secretion.

Famotidine is a histamine H2-receptor antagonist. Famotidine completely inhibits the action of histamine on H2-receptors of parietal cell. It inhibits basal, overnight and pentagastrin stimulated gastric acid secretion.

Adult Dose (Oral):

• Benign Gastric and Duodenal Ulcer: 40 mg daily at bedtime for 4-8 wk or 20 mg bid.
• Gastroesophageal Reflux Disease: 20 mg bid for 6-12 wk or up to 40 mg bid if esophageal ulceration.
• Zollinger-Ellison Syndrome: Initially 20 mg 6 hrly, up to 800 mg/day if necessary.
• Non-ulcer Dyspepsia, Heartburn: 10-20 mg once or bid.

Child Dose (1-16 years): Peptic Ulcer: 0.5 mg/kg PO at bedtime; max 40 mg/day.

Common Side Effects:

• Headache
• Diarrhea
• Constipation
• Nausea
• Vomiting
• Skin rash
• Dizziness
• Drowsiness

Use in Pregnancy: Famotidine is generally considered safe during pregnancy; animal studies have shown low or no adverse effects.

Precautions:

• Famotidine does not usually affect your ability to drive.
• Take with or without food.
• If taking antacids, take them 2 hours before or after Famotidine.
• Avoid soft drinks, citrus fruits (orange, lemon) which can irritate the stomach and increase acid secretion.
• Inform doctor if no improvement after 2 weeks.
• Inform doctor if diagnosed with kidney disease (dose may need adjustment).
• Do not stop taking without talking to your doctor.

Overdose: Limited information on overdose; symptomatic treatment.

Storage: Keep below 30 degree C, away from light and moisture. Keep out of reach of children.