Nax-N 250

Naproxen is a pain relieving medicine. It provides relief to pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and juvenile arthritis. It also helps in relieving muscle and joint pain, headache, toothache, and menstrual cramps. Naproxen should be taken with food to avoid stomach upset and reduce side effects. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as it will become less effective if you do. The common side effects of this medicine include vomiting, stomach pain, nausea, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. This medicine is generally considered safe but is not suitable for everybody. Before you take it, you should tell your doctor if you have kidney problems, asthma, blood disorders or drink a lot of alcohol. Also, tell your doctor what other medicines you are taking to make sure you are safe. It is best to avoid drinking alcohol while using this medicine. Naproxen is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

• Pain relief

Naproxen, a propionic acid derivative, is a prototypical NSAID. It reversibly inhibits the cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, thus resulting in reduced synthesis of prostaglandin precursors. It can inhibit platelet aggregation, has anti-inflammatory, analgesic and antipyretic actions.

Adult Dose: Adults Oral: Pain 500 mg PO initially, then 250 mg PO q6-8hr or 500 mg PO q12hr PRN; not to exceed 1250 mg/day naproxen base on day 1; subsequent daily doses should not exceed 1000 mg naproxen base Extended release: 750-1000 mg PO qDay; may temporarily increase to 1500 mg/day if tolerated well and clinically indicated Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis 500-1000 mg/day PO divided q12hr; may increase to 1500 mg/day if tolerated well for limited time Extended release: 750-1000 mg PO qDay; may temporarily increase to 1500 mg/day if tolerated well and clinically indicated Dysmenorrhea 500 mg PO initially, then 250 mg PO q6-8hr or 500 mg PO q12hr (long-acting formula); not to exceed 1250 mg/day on first day; subsequent doses should not exceed 1000 mg/day naproxen base Gout, Acute 750 mg PO initially, followed by 250 mg q8hr until attack subsides Extended release: 1000-1500 mg qDay, followed by 1000 mg qDay until attack subsides Child Dose: Pain >12 years 500 mg PO initially, then 250 mg PO q6-8hr or 500 mg PO q12hr PRN; not to exceed 1250 mg/day naproxen base on day 1; subsequent daily doses should not exceed 1000 mg naproxen base Extended release: 750-1000 mg PO qDay; may temporarily increase to 1500 mg/day if tolerated well and clinically indicated Juvenile Idiopathic Arthritis >2 years: 10 mg/kg/day oral suspension PO divided q12hr; not to exceed 15 mg/kg/day Renal Dose: Renal impairment: CrCl <30 mL/min: Use not recommended Severe: Contraindicated.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Naproxen is to be taken with food.

Common: • Vomiting • Nausea • Indigestion • Heartburn

[UNSAFE] Naproxen may cause side effects which could affect your ability to drive. Naproxen may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability. You have been prescribed Naproxen to relieve pain and inflammation. Take it with food or milk to prevent upset stomach. Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems. Do not take indigestion remedies (antacids) within two hours of taking Naproxen. Avoid consuming alcohol while taking Naproxen as it can increase your risk of stomach problems. Inform your doctor if you have a history of heart disease or stroke. Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Hypersensitivity. Aspirin or NSAID allergy. Perioperative pain in the setting of CABG surgery. Pregnancy (3rd trimester).

May enhance methotrexate toxicity. Reduced BP response to ACE inhibitors or angiotensin II receptor antagonists. Increased risk of serious GI events (e.g. ulcer) w/ aspirin. Increased risk of GI bleeding w/ warfarin. May reduce the natriuretic effects of furosemide or thiazide diuretics. May increase serum lithium concentrations and reduce renal lithium clearance. Delayed absorption w/ antacids, colestyramine or sucralfate. May interfere w/ the antihypertensive effects of beta-blockers (e.g. propranolol). May increase serum levels w/ probenecid.

[UNSAFE] It is unsafe to consume alcohol with Naproxen.

[CONSULT YOUR DOCTOR] Naproxen may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Naproxen is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

[CAUTION] Naproxen should be used with caution in patients with kidney disease. Dose adjustment of Naproxen may be needed. Please consult your doctor. [CAUTION] Naproxen should be used with caution in patients with liver disease. Dose adjustment of Naproxen may be needed. Please consult your doctor.

Migraine pain from 2 years I use tablet naprosyn 500 but not permanent relief Start tab topamac 25 mg hs Iam facing migraine since last 2 years and facing problem once in 2-3 days.taking naprosyn 250 and relief but need any permanent solution.pls guide. start tab topamac 25 mg at nite daily I have migraine and after 2 or 3 day pain starts.I have shown to Doctor he had proscribed me Naprosyn 250 then also my pain doesn&#x27;t ends.What to do for this headache Start tab topamac 25 mg daily for at least 2 to months Plz dr. suggest me periods pain reliefer tablet which available easily at store. You can take govern tablets for pain relief Dear doctor my wife is 4 month pregnant since afternoon she is suffering from head ache , can you please suggest me what should be done Tablet Crocin pain relief can. E given 35, Female, suffering from migraine Hello Doc, I am 35, Female, suffering from migraine from the past one year. Was taking Naprosyn 250mg whenever it started. It&#x27;s working fine with me but I heard that taking this tablet for long has side effects. Can you kindly suggest. Take topamac 25 mg hs What is treatment for chest chondritis i m feelin pain in chest while moving when i cansult to doctor he told me u rsuffering from chest chondritis he prescribed me naprosyn 500and hot water inflamation If the diagnosis is correct then its self limiting. Nothin to worry. Medcines prescribed are correct I have piles problem for last 30 days and i just want to know which medicine or tablet i should take right now which can relief my pain and bleeding. Kindly suggest me tablet zerodol for pain relief Sits bath Consult a surgeon Avoid constipation