osudhkosh
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Company•Popular Pharmaceuticals Ltd.

Neosuxa

100mg/2mlRx
Generic: Suxamethonium Chloride (Succinylcholine)

৳ 17.25/unit

Pack: ৳ 17.25

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At a glance

Suxamethonium Chloride (Succinylcholine) is a short-acting depolarizing neuromuscular blocking agent used for endotracheal intubation and skeletal muscle relaxation during general anesthesia.

Indications
  • Facilitate endotracheal intubation
  • Skeletal muscle relaxation during surgical and obstetric procedures
  • Assist mechanical ventilation
Pharmacology

Suxamethonium binds to nicotinic acetylcholine receptors at the neuromuscular junction, causing depolarization and muscle fasciculation. Unlike acetylcholine, it is hydrolyzed slowly by plasma cholinesterase (butyrylcholinesterase), preventing muscle cell resetting and maintaining muscle relaxation.

Dosage

Adult Dose (IV):

  • Intubation: 0.3-1.1 mg/kg (onset 30-60 seconds, duration 2-6 minutes)
  • Supplemental: 50-100% of initial dose at 5-10 minute intervals
  • Continuous infusion: 0.1-0.2% solution at 2.5-4 mg/min; max 500 mg/hour

Adult Dose (IM):

  • 3-4 mg/kg; max 150 mg

Pediatric Dose (IV):

  • Infants: 2 mg/kg; older children: 1 mg/kg
  • IM: 4-5 mg/kg (infants), 4 mg/kg (older children); max 150 mg
Side effects

Common Side Effects:

  • Bradycardia, tachycardia, hypertension, hypotension
  • Bronchospasm, prolonged respiratory depression
  • Muscle fasciculation, postoperative muscle pain
  • Hyperthermia, increased intraocular pressure
  • Rash, excessive salivation
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in genetic disorders of plasma pseudocholinesterase, personal/family history of malignant hyperthermia
  • Caution in severe burns, major trauma, extensive denervation of skeletal muscle, risk of hyperkalemia
  • Do not use in open eye injuries (increased intraocular pressure)
  • Do not use in neonates and premature infants
Overdose effects

Overdose may cause prolonged respiratory depression and paralysis; provide artificial respiration and supportive treatment.

Storage conditions

Store at 2-8°C in a refrigerator; do not freeze; keep out of reach of children.

Suxamethonium Chloride (Succinylcholine) — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.