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At a glance

Nepafenac Eye prep is an NSAID used for pain and inflammation associated with cataract surgery. It works by inhibiting prostaglandin biosynthesis.

Indications
  • Post-operative eye pain and inflammation following cataract surgery
  • Prevention of post-operative macular edema in diabetic patients
Pharmacology

Nepafenac is an NSAID prodrug converted to amfenac which inhibits prostaglandin biosynthesis to reduce eye pain and inflammation.

Dosage

Adult Dose (Eye Drops):

  • 0.1%: 1 drop 3 times daily, 1 day prior to cataract surgery, on day of surgery and through first 2 weeks
  • 0.3%: 1 drop once daily, 1 day before surgery, on day of surgery and through first 2 weeks; additional drop 30-120 minutes before surgery
  • Prevention of macular edema (0.1%): 1 drop 3 times daily, 1 day before surgery, on day of surgery and through first 6 weeks
Side effects

Common Side Effects:

  • Application site irritation
  • Eye irritation
  • Blurred vision
  • Watery or dry eyes
Use in pregnancy

Use in Pregnancy: Nepafenac may be unsafe during pregnancy; animal studies show evidence of fetal harm.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Consult doctor if no improvement in 2 weeks
  • Caution while driving or using machines (may cause blurred vision)
  • Inform doctor if on blood thinners or have bleeding problems
  • Use within 4 weeks of opening
Overdose effects

Limited information on overdose; symptomatic treatment.

Storage conditions

Store in a cool and dry place, away from light; keep out of reach of children.

Nepafenac Eye prep — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.