৳ 750/unit
Pack: ৳ 750
৳ 750/unit
Pack: ৳ 750
At a glance
Netarsudil + Latanoprost is an eye drop used for reducing elevated intraocular pressure (IOP) in open-angle glaucoma or ocular hypertension. Netarsudil is a Rho kinase inhibitor and Latanoprost is a Prostaglandin F2 analogue.
Indications
- Open-angle glaucoma
- Ocular hypertension
Pharmacology
Netarsudil inhibits Rho kinase to relax trabecular meshwork and inner wall of Schlemm's canal, decreasing episcleral venous pressure. Latanoprost acts as FP receptor agonist to increase uveoscleral outflow and reduce IOP.
Dosage
Adult Dose (Eye Drops):
- 1 drop in affected eye(s) once daily in the evening
Side effects
Common Side Effects:
- Conjunctival hyperemia (53%)
- Corneal verticillata (~20%)
- Instillation site pain
- Conjunctival hemorrhage
- Instillation site erythema (5-10%)
- Corneal staining
- Blurred vision
- Increased lacrimation
- Erythema of eyelid
- Reduced visual acuity
Use in pregnancy
Use in Pregnancy: No adequate controlled studies in pregnant women; systemic exposure from ocular administration is low.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in active intraocular inflammation (iritis/uveitis)
- May cause changes to pigmented tissues
- May gradually change eyelashes and vellus hair in treated eye
- Cystoid macular edema may occur
- Reactivation of Herpes Simplex keratitis may occur
Overdose effects
Limited information on overdose; symptomatic treatment.
Storage conditions
Before opening: Store at 2-8°C in a dry place, protect from light. After opening: May be kept at 2-25°C for up to 6 weeks.