৳ 600/unit
Pack: ৳ 600
৳ 600/unit
Pack: ৳ 600
At a glance
Netarsudil eye prep is used for reducing elevated intraocular pressure (IOP) in open-angle glaucoma or ocular hypertension. It is a dual inhibitor of Rho kinase and norepinephrine plasma membrane transport protein that increases trabecular outflow.
Indications
- Open-angle glaucoma
- Ocular hypertension
Pharmacology
Netarsudil inhibits Rho kinase to relax trabecular meshwork and inner wall of Schlemm's canal, decreasing episcleral venous pressure. It also inhibits norepinephrine plasma membrane transport protein to increase trabecular outflow.
Dosage
Adult Dose (Eye Drops):
- 1 drop in affected eye(s) once daily in the evening
Side effects
Common Side Effects:
- Hyperemia (53%)
- Corneal verticillata (~20%)
- Instillation site pain
- Conjunctival hemorrhage
- Instillation site erythema (5-10%)
- Corneal staining
- Blurred vision
- Increased lacrimation
- Erythema of eyelid
- Reduced visual acuity
Use in pregnancy
Use in Pregnancy: No data available on use in pregnant women; systemic exposure from ocular administration is low.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Risk of bacterial keratitis with multiple-dose containers (due to contamination)
- Caution in patients with corneal disease or disruption of ocular epithelial surface
Overdose effects
Limited information on overdose; symptomatic treatment.
Storage conditions
Before opening: Store at 2-8°C in a dry place, protect from light. After opening: May be kept at 2-25°C for up to 6 weeks.