৳ 4.25/unit
Pack: ৳ 42.50
৳ 4.25/unit
Pack: ৳ 42.50
At a glance
Mecobalamin is an active form of vitamin B12 used for peripheral neuropathy and megaloblastic anemia. It helps maintain myelin integrity, neuronal function, red blood cell formation, and DNA synthesis.
Indications
- Peripheral neuropathy
- Diabetic neuropathy
- Alcoholic neuropathy
- Drug-induced neuropathy
- Entrapment neuropathy
- Lumbago, intercostal neuralgia
- Diabetic retinopathy
- Multiple sclerosis
- Parkinson's disease, Alzheimer's disease
- Bell's palsy
- Megaloblastic anemia due to vitamin B12 deficiency
Pharmacology
Mecobalamin is the active coenzyme form of vitamin B12 that acts as a cofactor for methionine synthase enzyme. It helps maintain myelin integrity, neuronal function, and red blood cell formation.
Dosage
Oral (Adult): 1500 mcg/day in 3 divided doses, after meals
Injection (Adult):
- Peripheral neuropathy: 500 mcg IM/IV, 3 times weekly
- Megaloblastic anemia: 500 mcg IM/IV, 3 times weekly; after 2 months, maintenance: 500 mcg every 1-3 months
Side effects
Oral: Anorexia, nausea, vomiting, diarrhea
Injection: Rash, headache, hot sensation, diaphoresis, pain/induration at IM injection site
Potentially Fatal: Anaphylactoid reactions (parenteral)
Use in pregnancy
Use in Pregnancy: Limited data; however, vitamin B12 is generally considered compatible with breastfeeding.
Precautions & warnings
- Do not use for months if there is no response after a certain period
- Avoid prolonged large doses in patients handling mercury or mercury compounds
- Consult doctor during pregnancy and lactation
Overdose effects
No specific overdose information available; symptomatic and supportive treatment.
Storage conditions
Store at room temperature, protected from moisture and light; keep out of reach of children.