Neureliv 50

• Diabetic Neuropathy: Indicated for the improvement of subjective symptoms (numbness and pain), abnormality of vibration sense and abnormal change in heartbeat associated with diabetic peripheral neuropathy.

Adult Dose:

• Diabetic Neuropathy: 50 mg three times daily (before meals).

Dose Adjustment: Dosage may be adjusted according to the patient's age and symptoms.

Common Side Effects:

• Nausea
• Vomiting
• Abnormal liver function (elevated liver enzymes)

Other Side Effects:

• Malaise
• Headache
• Abdominal pain
• Hypersensitivity reaction
• Thrombocytopenia (rare)

Precautions:

• It is not known whether Epalrestat alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
• Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
• If you have existing diabetic nerve disease, wear proper footwear and examine your feet every day to detect lesions early.
• If you have a foot injury or open wound, avoid engaging in weight-bearing activities.
• The administration should be considered to patients showing high glycohemoglobin values even after fundamental therapies for diabetes mellitus.
• When efficacy is not observed even after 12 weeks of administration, other appropriate therapies should be taken.
• In cases of hepatic abnormalities, drug should be discontinued immediately and appropriate measures should be taken.