Nifetab SR20mg
Rx- Generic:
- Nifedipine
- Company:
- Drug International Ltd.
- Dosage form:
- Tablet
- Pack size:
- Box (100 Tablet)
৳ 0.54/unit
Pack: ৳ 54
At a glance
Nifedipine — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Nifedipine is a medicine used to treat high blood pressure (hypertension) and to prevent angina (heart-related chest pain). It belongs to a class of medicines known as calcium channel blockers. It lowers blood pressure and reduces the workload of the heart. This helps prevent heart attacks and strokes. Nifedipine may be prescribed alone or along with other medicines. The dose and how often you need it will be decided by your doctor so that you get the right amount to treat your condition. Your doctor may adjust the dose depending on how you respond to this medicine and your blood pressure levels. You can take it at any time of the day, with or without food, but it is best to take it at the same time each day. Take this medicine as soon as you have taken it out of the packet. It is sensitive to light and may not work properly if it is left out of the pack for too long. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine. The most common side effects include fatigue, swelling in the feet or ankles, dizziness, unusual heartbeat (palpitations), flushing, constipation, and headache. Consult your doctor if any of these bother you, or do not go away. Before taking it, let your doctor know if you have any heart, liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking, especially those used to treat high blood pressure or heart conditions. Avoid excessive alcohol intake while taking this medicine as it can significantly decrease your blood pressure and make you feel dizzy or light-headed. You should have your blood pressure checked regularly to make sure that this medicine is working properly. Nifedipine is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. The enhanced blood flow in the body further relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.
Indications
• Hypertension (high blood pressure) • Angina (heart-related chest pain)
Mechanism of action
Nifedipine prevents Ca ion from entering the slow channels of cardiac and smooth muscles during depolarisation, producing peripheral and coronary vasodilatation. It reduces afterload, peripheral resistance and BP; increases coronary blood flow and causes reflex tachycardia. It has little or no effect on cardiac conduction and rarely has negative inotropic activity.
Dosage
Adult Dose: Oral Hypertension Adult: Immediate-release: Initially, 5 mg tid. Maintenance: 10-20 mg tid. Extended-release: Initially, 10-40 mg bid, or 20-90 mg once daily. Angina pectoris Adult: Immediate-release: Initially, 10 mg tid. Maintenance: 10-20 mg tid. Extended-release: 10-40 mg bid or 30-60 mg once daily. Raynaud's syndrome Adult: Immediate-release: 5-20 mg tid. Elderly: Dose reduction may be necessary. Hepatic impairment: Dose reduction may be necessary.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nifedipine may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Nifedipine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Ankle swelling • Dizziness • Edema (swelling) • Fatigue • Flushing (sense of warmth in the face, ears, neck and trunk) • Headache • Palpitations
Precautions & warnings
[CAUTION] Nifedipine may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur. Nifedipine may make you feel dizzy, faint, extremely tired or have visual disturbances. This may affect your ability to drive. Take it at the same time every day to help you remember to take it. A sudden drop in your blood pressure may occur, especially when you first start taking Nicardia Retard 20 Tablet SR. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away. It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Nicardia Retard 20 Tablet SR affects you. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding.
Contraindications
Acute MI, cardiogenic shock, acute unstable angina, treatment of anginal attack in chronic stable angina.
Drug interactions
Enhanced antihypertensive effects w/ other antihypertensives, aldesleukin, and antipsychotics. Concomitant use w/ fentanyl during surgery caused severe hypotension. May modify insulin and glucose responses. Attenuation of tachycardic effect when used w/ benazerpril. Prothrombin time may be increased w/ coumarin anticoagulants. Increased serum levels w/ CYP3A4 inhibitors (e.g. azole antifungals, cimetidine, erythromycin, HIV-protease inhibitors, nefazodone, fluoxetine, quinupristin/dalfopristin). Potentially Fatal: Decreased bioavailability and efficacy w/ strong CYP3A4 inducers (e.g. rifampicin, phenytoin, carbamazepine).
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Nifedipine. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Nifedipine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Nifedipine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Nifedipine is safe to use in patients with kidney disease. No dose adjustment of Nifedipine is recommended. However, talk to your doctor if you have any underlying kidney disease. [CAUTION] Nifedipine should be used with caution in patients with liver disease. Dose adjustment of Nifedipine may be needed. Please consult your doctor.
Common questions
I am facing high blood pressure of160/100 for last 10-15 days. Should I start medication. Amiloz at or nicardia retard 20 tab. Which one is suitable. Send 3 BP readings on different days on a Doctors prescription pad Is Nicardia retard 10 safe in pregnancy Can be taken if required. What is heart attack? When heart attack coming? Related to chest pain angina commonly Why suggested me Nicardia retard 10 in 29th weeks of pragnancy? ushould ask the doctor who has prescribed it I am 21 weeks pregnant.from 14 weeks doctor prescribed me nicardia retard 10.my blood pressure is always in normal range 80 and 120.is it safe in pregnancy Yes it can be safely used in pregnancy With tab. Trimacsart OD and tab. Nicardia retard 10 mg OD my BP is 130/84. Some dr. Told that amlodipine salt and nicardia retard can't be taken together. May it taken together or not, pls tell. Both are same group medicine thatswhy should not be taken together I am 21 weeks pregnant.doctor prescribed me to take nicardia retarded 10 mg twice daily since 14 week.i have normal blood pressure 80 /120.MacDonald cervix stitch was happened 14 weeks.is nicardia safe in pregnancy Yes it can be taken if required. Generally given to relax the uterus in case you are at high risk of having preterm labour