৳ 35.11/unit
Pack: ৳ 35.11
৳ 35.11/unit
Pack: ৳ 35.11
At a glance
Nitazoxanide is an antiparasitic medication used for diarrhea and worm infections. It inhibits pyruvate:ferredoxin oxidoreductase (PFOR) enzyme to interfere with anaerobic metabolism of parasites.
Indications
- Diarrhea caused by Cryptosporidium parvum
- Diarrhea caused by Giardia lamblia
- Diarrhea caused by Entamoeba histolytica
Pharmacology
Nitazoxanide interferes with PFOR enzyme-dependent electron transfer reaction to block anaerobic energy metabolism of parasites, inhibiting parasite growth.
Dosage
Adult Dose (Oral):
- Giardiasis/Cryptosporidiosis: 500 mg every 12 hours for 3 days
Pediatric Dose:
- 1-3 years: 100 mg (5 ml) every 12 hours for 3 days
- 4-11 years: 200 mg (10 ml) every 12 hours for 3 days
- 12 years+: 500 mg every 12 hours for 3 days
Side effects
Common Side Effects:
- Abdominal pain
- Vomiting
- Headache
- Nausea
- Anorexia
- Flatulence
- Dizziness
- Abnormal liver function tests
Use in pregnancy
Use in Pregnancy: Nitazoxanide is safe during pregnancy (Category B); animal studies show low or no adverse effects.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in hepatic & biliary disease
- Caution in renal disease
- Caution during pregnancy and lactation
- Caution while driving (may cause dizziness and drowsiness)
Overdose effects
Limited information on overdose; symptomatic treatment.
Storage conditions
Store in a dry place, away from light and heat; keep out of reach of children.