৳ 45.17/unit
Pack: ৳ 180.68
৳ 45.17/unit
Pack: ৳ 180.68
At a glance
Sumatriptan is a serotonin (5-HT1B/1D) receptor agonist (triptan) used for the acute treatment of migraine with or without aura in adults.
Indications
- Acute treatment of migraine with or without aura – in adults
Pharmacology
Sumatriptan activates 5-HT1B receptors to constrict cranial arteries and 5-HT1D receptors to inhibit neurogenic inflammation in the trigeminal nerve. It reduces cranial vasodilation, decreases neuropeptide release, and relieves migraine pain, nausea, and sensitivity to light and sound.
Dosage
Adult Dose (Oral):
- 50-100 mg single dose; may repeat after 2 hours if migraine recurs
- Maximum: 200 mg/24 hours
- Mild-moderate hepatic impairment: Max single dose 50 mg
Nasal Spray:
- Single dose: 10 mg; maximum 30 mg/24 hours; separate doses by 1 hour
Side effects
Common Side Effects:
- Dizziness, weakness
- Drowsiness
- Peripheral neuropathy (tingling in hands and feet)
- Flushing (warmth in face, ears, neck)
- Nasal pain, burning (nasal spray)
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not use in history of coronary artery disease or coronary vasospasm
- Do not use in stroke, TIA, or hemiplegic/basilar migraine
- Do not use in uncontrolled hypertension
- Do not use in severe hepatic impairment
- Do not use as prophylactic therapy
Overdose effects
No overdose information available; excessive doses may increase side effects; provide symptomatic treatment.
Storage conditions
Store at 20-25°C; do not refrigerate or freeze; keep out of reach of children.