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At a glance

Sodium Chloride is a saline solution used for dehydration, electrolyte imbalance, nasal dryness, wound cleansing, and medication dilution. It restores the body's salt and electrolyte levels.

Indications
  • Dry nasal membranes (from cold and allergy medications)
  • Dry nose from dry climates or airplane travel
  • Wound cleansing (body parts and medical equipment)
  • Diluent for other medications
  • Metabolic alkalosis
  • Fluid replacement in gastroenteritis
  • Priming fluid for hemodialysis
  • Phlegm thinning in bronchiolitis, asthma, COPD (nebulizer)
  • Reducing corneal swelling (ophthalmic)
Pharmacology

Sodium Chloride is the major extracellular cation, important in electrolyte and fluid balance, osmotic pressure control, and water distribution. As a nasal drop, it moisturizes the nose and dissolves thick mucus. Intravenously, it provides hydration, treats metabolic alkalosis, and serves as a priming solution for hemodialysis.

Dosage

Nasal Drop (Nasal Congestion):

  • Infants, children & adults: 2 drops in each nostril, 1-4 times daily

Nasal Spray:

  • Newborn to 12 months: 1 spray into each nostril 2-3 times daily
  • >12 months & adults: 1-2 sprays into each nostril 2-3 times daily

Intravenous (Adult):

  • Usually 1000 ml of 0.9% solution (depends on age, weight, clinical condition)

Nebulizer:

  • 4 ml nebulized for 20 minutes, 4 times daily (all ages)
Side effects

Side Effects:

  • Nasal: Stinging, sneezing, increased nasal discharge, salty taste (occasional)
  • Intravenous: Fever, injection site infection, venous thrombosis, phlebitis, extravasation, hypervolemia
  • Ophthalmic: Temporary blurred vision, burning/irritation
Use in pregnancy

Use in Pregnancy: Safe when used as directed; use if clearly needed; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in heart disease (CHF), lung problems (pulmonary edema), kidney disease
  • Caution in hypokalemia and hypernatremia
  • Avoid excessive administration (may cause hypokalemia)
  • Do not use IV solution if cloudy or contains particles
Overdose effects

IV overdose may cause hypernatremia, hyperchloremia, and hypervolemia; provide symptomatic treatment.

Storage conditions

Store below 30°C in a dry place, protected from light; keep out of reach of children.

Sodium Chloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.