Novoseven 200IU1mg(5kiu)

• Bleeding in patients with haemophilia: Bleeding episodes and control of bleeding during surgery in haemophilia A or B patients.
• Bleeding due to factor VII deficiency: Bleeding control during surgery or invasive procedures in patients with factor VII deficiency.
• Glanzmann's thrombasthenia: Bleeding control during surgery or invasive procedures in patients with Glanzmann's thrombasthenia.

Adult Dose:

• Bleeding in haemophilia patients: 90 mcg/kg IV bolus (2-5 min); additional doses may be given 2-3 hrly as needed.
• Bleeding due to factor VII deficiency: 15-30 mcg/kg IV bolus (2-5 min) 4-6 hrly until haemostasis achieved.
• Glanzmann's thrombasthenia: 90 mcg/kg IV bolus (2-5 min) 2 hrly; give at least 3 doses.

Common Side Effects:

• Blood clot in the blood vessels (thromboembolic events)
• Nausea
• Vomiting
• Skin reactions
• Fever
• Headache
• Changes in blood pressure
• Anaphylaxis (rare)

Precautions:

• It is not known whether Eptacog Alfa alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
• Caution in advanced atherosclerotic disease, crush injury, septicemia or disseminated intravascular coagulation (DIC).
• Caution in patients with history of CHD, liver disease, undergoing major surgery, at risk of thromboembolic phenomena.
• Remote possibility of hypersensitivity to mouse IgG, bovine IgG & other residual culture proteins.
• Monitor prothrombin time & factor VII coagulant activity in factor VII deficient patients.