Oflacin 200
Rx- Generic:
- Ofloxacin
- Company:
- Drug International Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 12.05/unit
Pack: ৳ 120.50
At a glance
Ofloxacin — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Ofloxacin is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms. Ofloxacin should be used in the dose and duration as advised by your doctor. It may be taken with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. You may experience nausea and stomach pain as the side effects of this medicine. These are usually temporary and resolve on their own, but please consult your doctor if they bother you or persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools. You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction which needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue or face, shortness of breath or breathing problems. Special care should be taken in people with kidney problems while taking this medicine. Ofloxacin is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
Indications
• Bacterial infections
Mechanism of action
Ofloxacin is a fluoroquinolone which inhibits bacterial topoisomerase IV and DNA gyrase enzymes required for DNA replication, transcription, repair and recombination. It has activity against a wide range of gram-negative and gram-positive microorganisms.
Dosage
Adult Dose: Oral Bronchitis Exacerbation, Community Acquired Pneumonia, Skin & Skin Structure Infections Adult: 400 mg bid for 10 days. Uncomplicated gonorrhoea Adult: 400 mg as a single dose. Nongonococcal Cervicitis/Urethritis Adult: 400 mg daily in single or divided doses for 7 days. Uncomplicated Cystitis Adult: 200 mg bid for 3-7 days. Complicated UTIs Adult: 200 mg bid for 10 days. Pelvic inflammatory disease Adult: 400 mg bid for 10-14 days. Prostatitis Adult: Acute or chronic: 200 mg bid for 28 days. Intravenous Complicated urinary tract infections Adult: 200 mg daily by infusion over at least 30 min. Max: 400 mg bid infused over at least 1 hr. Lower respiratory tract infections; Septicaemia Adult: 200 mg bid by infusion over at least 30 min. Max: 400 mg bid infused over at least 1 hr. Skin and soft tissue infections Adult: 400 mg bid infused over at least 1 hr. Hepatic impairment: Severe: Reduce dose. Max: 400 mg daily. Child Dose: Not indicated Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation 20-50 Reduce dose by half 24 hrly following usual initial dose. <20 and patients on haemodialysis or peritoneal dialysis 100 mg 24 hrly following usual initial dose..
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ofloxacin may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Ofloxacin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Nausea • Stomach pain • Diarrhea
Precautions & warnings
[UNSAFE] Ofloxacin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Your doctor has prescribed Ofloxacin to cure your infection and improve symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Discontinue Ofloxacin and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations. Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Contraindications
Hypersensitivity to quinolones; pregnancy and lactation; prolongation of the QT interval; uncorrected hypokalaemia.
Drug interactions
Concomitant use of class IA (e.g. quinidine, procainamide) or class III (e.g. amiodarone, sotalol) antiarrhythmic agents may increase risk of QT interval prolongation. Decreased serum and urine concentrations w/ antacids containing Mg, Al or Ca. Additive antibacterial activity w/ aminoglycosides (e.g. amikacin, tobramycin). Corticosteroids may increase risk of severe tendon disorders. Increased risk of CNS stimulation (e.g. seizures) w/ NSAIDs. Higher and prolonged serum theophylline concentrations and increased risk of theophylline-related adverse effects.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Ofloxacin.
Use in pregnancy
[CONSULT YOUR DOCTOR] Ofloxacin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Ofloxacin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CAUTION] Ofloxacin should be used with caution in patients with kidney disease. Dose adjustment of Ofloxacin may be needed. Please consult your doctor. [CAUTION] Ofloxacin should be used with caution in patients with liver disease. Dose adjustment of Ofloxacin may be needed. Please consult your doctor.
Common questions
I have indigestion problems Loose motions from last night & I am getting headache & General weakness Take oflox oz BD PATIENT is suffering from.diabetes.last week it was 159 in fasting. Though it was within normal range prior to this. She face sudden increase in blood sugar even with a little amount of rice that too without starch.she face some sort of shivering in her body and frequent urination in the night.she is taking G2 medicine as recommended.and all sort of yoga, walk and avoid oil n spices. But this shivering and frequent urination is quite troublesome for her, as there is no improvement in it.plz.suggest Start oflox ornidazole antibiotic I am suffering from loose motions. 2 -3 episodes since morning. Which medicine should i take?? Tab oflox oz BD for 5days I have a boil inside my left nose This is from day before yesterday and paining also facing pain in left face including tooth. Tab oflox BD for 5days I am having stomach pain and lose motion since 2 day I had taken norflox 400 mg I have bit relief in lose motion but stomach pain not gone completely. Kindly suggest some medicine Tab oflox oz BD Cap enterogermina BD Go to toilet in short interbell Take oflox oz twice for 5days. I am facing frequent vomits and slight fever with loose motion. Please help which medicine should I take. Feeling weakness Is there anyone available to help me. Tab oflox OZ BDBD for 5 days 3 episodes of loose stools and 1 vomiting Swallowed public pool water while swimming. Take oflox Oz for 5days two times daily