৳ 1,170/unit
Pack: ৳ 1,170
৳ 1,170/unit
Pack: ৳ 1,170
At a glance
Ofloxacin 0.3% E/E drops is an antibiotic used for bacterial eye infections, corneal ulcer, chronic suppurative otitis media and otitis externa. It inhibits bacterial DNA gyrase enzyme to prevent bacterial division and repair.
Indications
- Bacterial conjunctivitis
- Keratoconjunctivitis
- Corneal ulcer
- Chronic suppurative otitis media (with perforated tympanic membranes)
- Otitis externa
Pharmacology
Ofloxacin inhibits bacterial topoisomerase IV and DNA gyrase enzymes to prevent DNA replication, transcription, repair and recombination, resulting in bacterial cell death.
Dosage
Eye Drops (Adult):
- Bacterial conjunctivitis: 1-2 drops every 2-4 hours (first 2 days), then 4 times daily; max 10 days
- Corneal ulcer: Days 1-2: 1-2 drops q30min while awake; Days 3-7: 1-2 drops q1hr; Days 7-9: 4 times daily
Ear Drops:
- Chronic suppurative otitis media (12 years+): 10 drops twice daily for 14 days
- Otitis externa: 10 drops once daily for 7 days; (6 months-13 years: 5 drops once daily)
Side effects
Common Side Effects:
- Eye discomfort
- Eye irritation
- Eye pain
- Blurred vision
Use in pregnancy
Use in Pregnancy: Ofloxacin eye/ear drops may be unsafe during pregnancy; animal studies show evidence of fetal harm.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not wear contact lenses until infection clears
- Apply pressure on corner of eye (near nose) for 1 minute after instillation
- Use within 4 weeks of opening
- Caution while driving (may cause blurred vision)
Overdose effects
Overdose unlikely (topical use); symptomatic treatment.
Storage conditions
Store at room temperature; protect from light; keep out of reach of children.