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Olanzapine is a prescription medicine used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. Olanzapine may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include dryness in mouth, constipation, muscle rigidity and restlessness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, this medicine may increase your weight, blood sugar and cholesterol levels but, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect. You should be cautious as in rare cases it may cause serious side effects like very high blood sugar levels or seizures. Olanzapine is an atypical antipsychotic. It works by affecting the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts and behavior.

• Schizophrenia • Mania

Olanzapine is an atypical antipsychotic with affinity for serotonin 5-HT2A/2C, dopamine, muscarinic M1-M5, histamine H1 and adrenergic alpha1 receptors.

Adult Dose: Oral Schizophrenia Adult: 5-10 mg/day initially; if necessary, may be titrated upward in increments of 5 mg/day at intervals >1 week Maintenance: 10-20 mg/day; not to exceed 20 mg/day Bipolar Mania Used as monotherapy or in combination with lithium or valproate Monotherapy: 10-15 mg/day PO initially Adjunct to lithium or valproate: 10 mg/day PO initially Maintenance: 5-20 mg/day PO; not to exceed 20 mg/day Depression in bipolar disorder Use in combination with fluoxetine 5 mg in evening; adjusted to range of 5-12.5 mg/day; may be increased up to 20 mg/day in resistant depression Hepatic impairment: Initial: 5 mg daily. Child Dose: Oral Bipolar I Disorder (Manic or Mixed Episodes) <13 years: Safety and efficacy not established 13-17 years: 2.5-5 mg/day PO initially; target dosage, 10 mg/day; adjust by increments/decrements of 2.5-5 mg; dosage range, 2.5-20 mg/day Schizophrenia <13 years: Safety and efficacy not established 13-17 years: 2.5-5 mg/day PO initially; target dosage, 10 mg/day; adjust by increments/decrements of 2.5-5 mg; dosage range, 2.5-20 mg/day Renal Dose: Renal impairment: Initial: 5 mg daily.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olanzapine may be taken with or without food, but it is better to take it at a fixed time.

Common: • Dizziness • Sleepiness • Orthostatic hypotension (sudden lowering of blood pressure on standing) • Dryness in mouth • Weight gain • Increased prolactin level in blood • Constipation • Muscle stiffness • Restlessness • Tremor

[UNSAFE] Olanzapine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Olanzapine works well in schizophrenia and bipolar disorder. It is less likely to cause heart and movement problems as compared to other similar medicines. It may take 4 to 6 weeks to see full effects on thoughts and mood. Keep taking it as prescribed. Use caution while driving or doing anything that requires concentration as Olanzapine can cause dizziness and sleepiness. It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Do not stop taking Olanzapine without talking to your doctor first as it may cause worsening of symptoms.

Angle-closure glaucoma; lactation. IM: History of CVS disease, heart surgery.

Olanzapine may antagonise the effects of levodopa and dopamine agonists. Drugs that induce CYP1A2 or glucuronyl transferase enzymes e.g. omeprazole and rifampicin, may increase olanzapine clearance. Inhibitors of CYP1A2 may potentially inhibit olanzapine elimination. Carbamazepine may increase the clearance of olanzapine. Concomitant admin of activated charcoal reduced the oral bioavailability of olanzapine by 50-60%. Caution should be taken when olanzapine is administered with centrally acting drugs and alcohol.

[UNSAFE] It is unsafe to consume alcohol with Olanzapine.

[CONSULT YOUR DOCTOR] Olanzapine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Olanzapine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Olanzapine is safe to use in patients with kidney disease. No dose adjustment of Olanzapine is recommended. [SAFE IF PRESCRIBED] Olanzapine is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Olanzapine may not be needed in these patients. Please consult your doctor.

My father has parkinson's disease from last 12 year. In last 2012 he got severe pneumonia and has been admitted in AIIMS .He was treated with various antibiotics.he came out but got bed ridden after that.From last few year he just sit on his own. he is currently taking bexol 1mg three times, syndopa 125 plus 3 times, ropark XL 3 times.now from few year he got hallucination and cound not sleep in night and constantly talking in night(Some Nights not always).During his stay in AIIMS Dr. prescribed quetiapine 12.5 mg which he is not currently taking.please advice some medicien so that he atleast can sleep at night. Start Oleanz 2.5 mg at nite How to control alcoholic halogination Try oleanz 2.5 mg bd HE HAD A BRAIN HAMMERAGE AND THEN HE WAS OPERATED.AFTER SURGERY HE IS GOING THROUGH RESTLESSNESS.PLEASE SUGGEST WHAT TO DO. Show to local Try tab Oleanz. 2.5 mg at nite I am 32 years old Male. I am suffering from movement disorder.disorder from last 8-10 years that is sometimes (not all times duration between 2 attacks may be alternate day to month to years) I have to move my limbs in awkward direction rapidly. It (involuntarily movements) can affect all my body parts including head which is worst. I feel so much pressure/urge in my head that i have to rotate my head clockwise/anticlockwise. All these are temporarily suppressible. My stress is manageable. Sleep is proper. No family history for this. No drinking, no smoking. No Fits, Convulsions. CT Scan/MRI Scan/EEg Normal.I have consulted Neurologist and was told that this may be TICS and prescribed REVOCON (TETRABENZINE). But this is not helping me. So please guide me If it is indeed tics Try tab Oleanz 2. 5 mg bd Plz sarach this sickness plzzzz PATIENT my friend.his body automatically moving and slow slow weak his health.now he is very weak he not eating any thing Before ten years his father also died same problem.dawinder is also last stage now.and now his little bro his age 27 year he is also in same sickness plz search this sickness.we can coming for treatment everywhere in india SADLY, NO definite cure' u can try tab oleanz 5 mg twice a day I have Schizophrenia, want buy oleanz 10mg 200tablets, can you give me a precription to my email I am from hongkong, I have friend live in india, so I want buy medicine from 1mg.com, but It need prescription, We understand your problem. But without examining patient Indian law does not allow prescribing medication. My apologies for same ? use lithosun sr ; Tegrital cr 400; oleanz 5 before 8 years ? want to ask is there Any side effect. You need regular blood tests for Kidney,Thyroid,Sugar and lipids and follow up with your psychiatrist ensures that side effects can be handled before they become severe. I have been taking Oleanz 5 and AMAZEO od 200 for the last 6 years. If i continue the same, any problem rises sir. Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you. Pay Rs 99 and call me on my phone www.dontfeel.com for counselling