৳ 15/unit
Pack: ৳ 15
৳ 15/unit
Pack: ৳ 15
At a glance
Active Vitamin D3 analogue indicated for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in chronic renal failure.
Indications
Indicated in adult patients with chronic renal failure for the management of hypocalcemia, secondary hyperparathyroidism, and renal osteodystrophy.
Pharmacology
Alfacalcidol stimulates intestinal calcium and phosphorus absorption, bone calcium reabsorption, and renal calcium conservation. It reduces elevated plasma PTH levels and relieves bone pain in chronic kidney disease.
Dosage
Initial Dose: 0.25 mcg/day for first 2 months. Can be titrated by 0.25 mcg/day every 2 months. Maintenance Dose: 0.5 mcg to 1 mcg/day. Reduce dose by 50% if hypercalcemia develops.
Side effects
Hypercalcemia, elevated BUN, dry mouth, metallic taste, nausea, vomiting, constipation, headache, anorexia, pruritus, bone pain, and hypertension.
Use in pregnancy
Avoid during pregnancy unless clearly needed. Hypercalcemia during pregnancy can cause congenital disorders.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Regular monthly monitoring of serum calcium and phosphate levels is required. Caution in patients with history of renal calculi.
Overdose effects
Discontinue drug and all calcium supplements immediately upon signs of hypercalcemia. Rehydrate patient as needed.
Storage conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.