Opsonil50mg/2ml
Rx- Generic:
- Chlorpromazine Hydrochloride
- Company:
- Opsonin Pharma Limited
- Dosage form:
- Injection
- Pack size:
- 1 amps
৳ 4/unit
Pack: ৳ 4
At a glance
Chlorpromazine Hydrochloride is a phenothiazine neuroleptic used for the treatment of schizophrenia, psychoses, mania, anxiety, nausea, vomiting, and intractable hiccups.
Indications
- Schizophrenia and other psychoses (especially paranoid)
- Mania and hypomania
- Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behavior
- Intractable hiccup
- Nausea and vomiting of terminal illness
- Childhood schizophrenia and autism
Dosage
Adult Dose (Schizophrenia, Psychosis - Oral): Initial: 30-75 mg/day divided q6-12hr; Maintenance: usually 200 mg/day (up to 800 mg/day in some patients; some may require 1-2 g/day).
Adult Dose (Parenteral): 25 mg initially, then 25-50 mg after 1-4 hours, then up to 400 mg q4-6hr until controlled; usual 300-800 mg/day.
Nausea & Vomiting: Oral: 10-25 mg q4-6hr; Parenteral: 25-50 mg q4-6hr.
Preoperative Apprehension: 25-50 mg PO (2-3 hours before) or 12.5-25 mg IM (1-2 hours before).
Intractable Hiccups: 25-50 mg PO q6-8hr; if persists after 2-3 days, 25-50 mg IM q3-4hr; if persists, slow IV infusion.
Pediatric Dose (>6 months): Behavioral disorders: 50-100 mg/day; Nausea: 0.5-1 mg/kg q6-8hr; Preoperative: 0.55 mg/kg 1-2 hours before surgery. <6 months: Safety and efficacy not established.
Elderly: Initial: 1/3-½ of normal adult dose.
Side effects
Common Side Effects:
- Sleepiness
- Orthostatic hypotension
- Dry mouth
- Abnormality of voluntary movements
- Weight gain
- Increased prolactin level
- Urinary retention
- Constipation
- Muscle stiffness
Rare Side Effects: Nasal congestion, blurred vision, nausea, libido changes, gynecomastia, skin/corneal pigmentation, photosensitivity, blood dyscrasias, leukopenia, eosinophilia, ECG changes, cholestatic jaundice, QT prolongation, lowered seizure threshold.
Precautions & warnings
- [UNSAFE] Chlorpromazine Hydrochloride may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
- Take it at night to avoid sleepiness during the day.
- Do not stop suddenly without talking to your doctor.
- Do not drink alcohol as it can cause serious breathing problems.
- Inform your doctor if you notice involuntary muscle movements.
- Monitor your weight during treatment.
- Rise slowly if you have been sitting or lying down.