৳ 8/unit
Pack: ৳ 8
৳ 8/unit
Pack: ৳ 8
At a glance
Etodolac is a pain relieving medicine used for the treatment of osteoarthritis, rheumatoid arthritis and acute pain.
Indications
- Osteoarthritis: Used for acute and long-term management of signs and symptoms.
- Rheumatoid Arthritis: Used for acute and long-term management of signs and symptoms.
- Acute Pain: Used for management of acute pain.
- Acute Gout: Used for treatment of gout.
Pharmacology
Etodolac is an NSAID derived from pyrano-indoleacetic acid, inhibits cyclooxygenase 2 (COX-2) resulting in decreased prostaglandin precursor formation. Similar to other NSAIDs, the anti-inflammatory effects of etodolac result from inhibition of the enzyme cyclooxygenase (COX). This decreases the synthesis of peripheral prostaglandins involved in mediating inflammation.
Dosage
Adult Dose (Oral):
- Osteoarthritis, Rheumatoid Arthritis: 600-1000 mg/day in divided doses; Max: 1200 mg/day.
- ER tablet: Once daily.
- Acute Gout: As needed.
Child Dose (Juvenile Rheumatoid Arthritis): >=60 kg: 1000 mg PO once daily (ER).
Hepatic impairment: Dose adjustment not necessary.
Side effects
Common Side Effects:
- Vomiting
- Stomach pain/epigastric pain
- Nausea
- Indigestion
- Loss of appetite
- Diarrhea
- Heartburn
- Flatulence
- Constipation
Others: Dizziness, edema, elevated liver enzymes, increased bleeding time, pruritis, rash, tinnitus.
Use in pregnancy
Use in Pregnancy: Etodolac may be unsafe; animal studies have shown harmful effects on the developing baby.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Etodolac may decrease alertness, affect vision or make you feel sleepy and dizzy; do not drive if these symptoms occur.
- Prescribed for relief of pain and inflammation.
- Take with food or milk to prevent upset stomach.
- Long term use may lead to stomach bleeding and kidney problems.
- Avoid alcohol (can cause excessive drowsiness and increase risk of stomach problems).
- Inform doctor if you have a history of heart disease or stroke.
- Your doctor may regularly monitor kidney function, liver function and blood components for long-term treatment.
Overdose effects
Overdose: Symptoms following acute NSAID overdose: lethargy, drowsiness, nausea, vomiting, epigastric pain; generally reversible with supportive care.
Storage conditions
Storage: Do not store above 30 degree C. Keep away from light and out of reach of children.