Ovel TS1.50%

Levofloxacin 1.5% Eye prep is an antibiotic, used in the treatment of bacterial infections of the eye. It relieves the symptoms of the infection by stopping the further growth of the causative microorganisms. Levofloxacin 1.5% Eye prep is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. Avoid skipping any doses and finish the full course of treatment even if you feel better. It may cause eye irritation and burning sensation in the eyes immediately following application. However, these side effects are temporary and usually subside on their own. Inform your doctor if they persist for a longer duration. It may cause short term blurring of vision when first used. Use caution before driving or using machines. Do not wear contact lenses while using it. Levofloxacin 1.5% Eye prep is an antibiotic. It treats bacterial eye infections by preventing the bacteria from dividing and repairing. It does so stopping the action of a bacterial enzyme called DNA-gyrase.

• Bacterial eye infections

Levofloxacin exerts antibacterial action by inhibiting bacterial topoisomerase IV and DNA gyrase, the enzymes required for DNA replication, transcription repair and recombination. It has in vitro activity against a wide range of gram-negative and gram-positive microorganisms.

Adult Dose: Ophthalmic Bacterial corneal ulcer Adults: Days 1 through 3: Instill one to two drops in the affected eye(s) every 30 minutes to 2 hours while awake and approximately 4 and 6 hours after retiring. Day 4 through treatment completion: Instill one to two drops in the affected eye(s) every 1 to 4 hours while awake. Child Dose: Ophthalmic Bacterial corneal ulcer Children 6 year of age and older: Days 1 through 3: Instill one to two drops in the affected eye(s) every 30 minutes to 2 hours while awake and approximately 4 and 6 hours after retiring. Day 4 through treatment completion: Instill one to two drops in the affected eye(s) every 1 to 4 hours while awake.

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

If you miss a dose of Levofloxacin 1.5% Eye prep, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Eye irritation • Burning sensation

[UNSAFE] Levofloxacin 1.5% Eye prep may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Levofloxacin 1.5% Eye prep for the treatment of bacterial infections of the eye. Do not skip any doses and finish the full course of treatment even if you feel better. Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the medication. Do not touch the tip to any surface, or to your eye, to avoid contamination. Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution. It may cause short term blurring of vision when first used. Use caution before driving or using machines. Do not wear contact lenses until your infection clears up. Make sure to use within 4 weeks of opening the medication.

Levofloxacin is contraindicated in patients with a history of hypersensitivity to Levofloxacin, quinolone, or any other components of this product.

Additive effects on QT interval prolongation w/ class IA (e.g. quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmics, fluoxetine or imipramine. Reduced absorption w/ sucralfate, didanosine, antacids containing Mg or Al, dietary supplements containing Zn, Ca, Mg or Fe. Altered glucose levels w/ antidiabetic agents (e.g. insulin, glibenclamide). Increased risk of severe tendon disorders w/ corticosteroids. Increased risk of CNS stimulation and seizures w/ NSAIDs. Increased prothrombin time w/ warfarin.

No interaction found/established

[CONSULT YOUR DOCTOR] Levofloxacin 1.5% Eye prep is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[CONSULT YOUR DOCTOR] Levofloxacin 1.5% Eye prep is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

No interaction found/established No interaction found/established

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