Oxigel Wash 5%
Rx৳ 400/unit
Pack: ৳ 400
৳ 400/unit
Pack: ৳ 400
At a glance
Benzoyl Peroxide 5% + Erythromycin 3% Topical is a combination medicine used for the treatment of acne vulgaris. Benzoyl Peroxide has keratolytic and antimicrobial properties, while Erythromycin stops bacterial protein synthesis. Together, they destroy acne-causing bacteria (Propionibacterium acnes) and help remove dead skin cells. It should be applied twice daily (morning and evening) to affected areas after cleaning and drying the skin. In Bangladesh, it is available under various brand names.
Indications
Used for the treatment of acne vulgaris.
Pharmacology
Benzoyl Peroxide has mild keratolytic effect and antimicrobial activity attributed to its oxidative property. It is active against S.epidermidis and P.acne. Erythromycin inhibits protein synthesis by irreversibly binding to the 50S ribosomal subunit, blocking transpeptidation or translocation reactions, resulting in stunted cell growth.
Dosage
Adult Dose: Adult: Topical Acne: Apply topically BID (morning and evening). Child Dose: 12 years: Apply topically BID (morning and evening)
Side effects
1-10% Dry skin (5-7.6%),Application site reaction (stinging, erythema, burning) (0.8-2.5%),Blepharitis (1.7%),Pruritus (1.7-2.5%),Photosensitivity (1.3%) <1% Skin peeling (<0.5%)
Use in pregnancy
There are no well-controlled trials in pregnant women with this therapy. It is not known whether this therapy can cause fetal harm or affect reproductive capacity. This therapy should be given to a pregnant woman only if clearly needed (Pregnancy Category: C). Animal reproduction studies have not been conducted
Precautions & warnings
Apply carefully near the eyes, mouth, neck and other mucous membranes as well as other sensitive areas. Discontinue if severe irritation develops. This medication should not be used for any disorder other than that for which it was prescribed. Topical gel may bleach hair or colored fabric. Concomitant topical acne therapy may result in cumulative irritation, especially with peeling, desquamating, or abrasive agents. If superinfection occurs, discontinue use and take appropriate measures.
Overdose effects
Topical overdose may cause excessive skin irritation, redness, dryness, and peeling. If you apply too much, wash the skin thoroughly and contact a doctor.
Storage conditions
Store below 30°C, protected from light and moisture. Keep out of reach of children. Do not use after the expiry date.