Pazocent 200
Rx- Generic:
- Pazopanib Hydrochloride
- Company:
- Incepta Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Box (10 Tablet)
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৳ 250/unit
Pack: ৳ 2,500
Price comparison
- This brand
- ৳ 250
- Cheapest of this genericPazonib
- ৳ 1
The cheaper brand costs ৳ 249.00 less per unit
Compared against 3 brands
At a glance
Pazopanib Hydrochloride is a multi-tyrosine kinase inhibitor used for the treatment of advanced renal cell carcinoma (RCC) and advanced soft tissue sarcoma (STS) who have received prior chemotherapy.
Indications
- Advanced Renal Cell Carcinoma (RCC)
- Advanced Soft Tissue Sarcoma (STS) with prior chemotherapy
Dosage
Adult Dose (Oral):
- Recommended dose: 800 mg once daily on an empty stomach (at least 1 hour before or 2 hours after a meal)
- Dose should not exceed 800 mg
- Do not crush tablets (may affect absorption rate)
- Hepatic impairment: Bilirubin >1.5-3 x ULN: Decrease dose to 200 mg/day; Bilirubin >3 x ULN: Not recommended
Pediatric Dose: Safety and efficacy not established.
Side effects
Common Side Effects:
- Hepatotoxicity (elevated ALT, AST, bilirubin)
- QT prolongation
- Cardiac dysfunction
- Hemorrhagic events
- Arterial and venous thromboembolic events
- Hypertension
- Hypothyroidism
- Proteinuria
- Diarrhea
- Nausea
- Vomiting
- Fatigue
- Headache
- Decreased appetite
- Weight loss
- Taste changes
- Hair discoloration
- Abnormal skin pigmentation
Precautions & warnings
- Hepatotoxicity can be severe and fatal; patients >65 years at greater risk; transaminase elevations occur within first 18 weeks
- QT prolongation and Torsades de Pointes; caution with history; monitor electrolytes
- May decrease alertness, affect vision, or cause sleepiness and dizziness; do not drive if these occur
- May cause serious bleeding problems; inform doctor if blood in urine or stools
- May affect wound healing; inform doctor before surgery
- Do not use during pregnancy or breastfeeding; use effective contraception
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.