৳ 10/unit
Pack: ৳ 10
৳ 10/unit
Pack: ৳ 10
At a glance
Pioglitazone is an anti-diabetic medication used to control type 2 diabetes mellitus in adults. It increases the body's sensitivity to insulin, helping to control blood sugar levels.
Indications
- Type 2 diabetes mellitus
Pharmacology
Pioglitazone activates PPAR-γ receptors, which increase expression of genes regulating lipid and glucose metabolism. It improves insulin sensitivity and reduces hepatic glucose production, resulting in lower blood sugar levels.
Dosage
Adult Dose (Oral):
- Type 2 diabetes: 15 mg once daily
- Elderly: No dosage adjustment needed
- Renal impairment: No dosage adjustment needed
- Hepatic impairment (moderate-severe): Avoid
Side effects
Common Side Effects:
- Weight gain
- Blurred vision
- Respiratory tract infection
- Numbness
- Bone fracture
- Peripheral edema
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy; animal studies have shown harmful effects; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Does not usually affect driving ability
- Do not use in heart failure or history, type 1 diabetes, diabetic ketoacidosis
- Inform doctor if shortness of breath, heart problems, or abnormal swelling occurs
- Monitor liver function; inform doctor if abdominal pain, yellowing of eyes, loss of appetite
- Not recommended in dialysis patients
Overdose effects
Overdose: May cause hypoglycemia; treatment: symptomatic; glucose administration; consult your doctor.
Storage conditions
Store in a cool and dry place; keep out of reach of children.