Pegin180mcg/vial
Rx- Generic:
- Peginterferon Alfa-2a
- Company:
- Beacon Pharmaceuticals PLC
- Dosage form:
- Injection
- Pack size:
- Injection
Save to my medicines
Alert me on price drop
৳ 9,800/unit
Pack: ৳ 9,800
Price comparison
- This brand
- ৳ 9800
This is the cheapest brand of this generic
Compared against 2 brands
At a glance
Peginterferon Alfa-2a is an interferon protein bound to polyethylene glycol used for the treatment of chronic hepatitis C and chronic hepatitis B.
Indications
- Chronic hepatitis C (compensated liver disease)
- Chronic hepatitis B (HBeAg positive and negative)
Dosage
Adult Dose (Subcutaneous):
- Chronic hepatitis C: 180 mcg once weekly for 48 weeks (monotherapy) OR with ribavirin (Genotypes 1 & 4: 48 weeks; Genotypes 2 & 3: 24 weeks)
- Chronic hepatitis B: 180 mcg once weekly for 48 weeks
- Dose modifications: Neutropenia (ANC <750: 135 mcg; <500: discontinue), Thrombocytopenia (Platelets <50,000: 90 mcg; <25,000: discontinue), Hepatic (ALT rise: 135 mcg; continued rise or bilirubin increase: discontinue)
Pediatric Dose (>5 years): 180 mcg/1.73 m² once weekly with ribavirin; Genotypes 2,3: 24 weeks; Genotypes 1,4: 48 weeks
Side effects
Common Side Effects (>10%):
- Fatigue (24-67%)
- Headache (27-54%)
- Fever (24-54%)
- Myalgia (26-51%)
- Influenza-like illness (25-47%)
- Neutropenia (21-40%)
- Anxiety (19-33%)
- Irritability (19-33%)
- Diarrhea (11-31%)
- Insomnia (19-30%)
- Arthralgia (22-28%)
- Alopecia (18-28%)
- Nausea and vomiting (5-25%)
- Loss of appetite (16-24%)
- Depression (18-20%)
- Anemia (2-14%)
Precautions & warnings
- Neuropsychiatric disorders: Discontinue treatment with worsening or persistently severe signs/symptoms
- Myelosuppression, anemia (spherocytosis, history of GI bleeding)
- Caution in pulmonary disease, autoimmune disease, cardiovascular disease, diabetes, thyroid disorders
- More frequent monitoring of LFTs and dose reduction in Hepatitis B
- May affect ability to drive or operate machinery
- Hazardous agent; handle and dispose appropriately
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.