Perkirol 2
Rx- Generic:
- Ropinirole
- Company:
- Square Pharmaceuticals PLC.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 6.04/unit
Pack: ৳ 60.40
At a glance
Ropinirole — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Ropinirole is a prescription medicine used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements. Ropinirole should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor. Some common side effects of this medicine include headache, fainting, vomiting, weakness, nausea, edema (swelling), abnormality of voluntary movements and dyspepsia (indigestion). It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble or uncontrolled spending as these may prove very harmful. Ropinirole works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.
Indications
• Parkinson's disease • Restless leg syndrome
Mechanism of action
Ropinirole is a non-ergot dopamine D2-agonist with similar actions to those of bromocriptine. It is used in the management of Parkinson's disease, either alone or as an adjunct to levodopa.
Dosage
Adult Dose: Oral As monotherapy in Parkinson's disease Adult: Initially, 250 mcg tid, may increase by 750 mcg at wkly intervals for the first 4 wk. Subsequent increments can be made in steps of 1.5 mg at wkly intervals up to 9 mg/day, then in steps of 3 mg at wkly intervals. Usual dose ranges from 3-9 mg daily. Max: 24 mg/day. Higher dose may be necessary if used in conjunction with levodopa. Gradual withdrawal is recommended. Restless leg syndrome Adult: Initially, 250 mcg daily for 2 days, taken 1-3 hr before bedtime. May increase to 500 mcg daily for the next few days. Subsequent increments may be made in steps of 500 mcg at wkly intervals until 3 mg daily is reached. Max: 4 mg daily. Hepatic impairment: Dosing adjustments may be required.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ropinirole is to be taken with food.
Side effects
Common: • Headache • Dizziness • Fainting • Sleepiness • Vomiting • Weakness • Nausea • Edema (swelling) • Abnormality of voluntary movements • Indigestion • Hallucination • Confusion • Viral infection
Precautions & warnings
[UNSAFE] Ropinirole may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Ropinirole to treat your symptoms of Parkinson's disease and/or restless leg syndrome. It can be taken with or without food. Taking it with food may reduce nausea. For restless leg syndrome, take this medicine 2 to 3 hours before bedtime. Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you. When you first start taking Ropinirole, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges. Talk to your doctor in case you develop hallucinations or other changes in your behavior. Do not stop taking the medication suddenly without talking to your doctor.
Contraindications
Lactation.
Drug interactions
Inhibitors of CYP1A2 e.g. cimetidine, ciprofloxacin, erythromycin, fluvoxamine, isoniazid, ritonavir and zileuton may increase serum concentrations of ropinirole. Oestrogens and tobacco smoking may decrease clearance of ropinirole. Efficacy may be reduced by dopamine antagonists such as phenothiazines and metoclopramide.
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Ropinirole. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Ropinirole may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Ropinirole is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Ropinirole suppresses serum prolactin and may interfere with breastfeeding.
Renal / hepatic impairment
[CAUTION] Ropinirole should be used with caution in patients with severe kidney disease. Dose adjustment of Ropinirole may be needed. Please consult your doctor. [CAUTION] Ropinirole should be used with caution in patients with liver disease. Dose adjustment of Ropinirole may be needed. Please consult your doctor. Use of Ropinirole is not recommended in patients with the severe liver disease.
Common questions
Is there have any medicine 4 PD Hi sir ,good afternoon My father is suffering from Parkinson's disease since last 3years. Recently he is taking syndopa plus revemer 3,Ropark 25 and amantrel I am not getting any positive results https://www.1mg.com/otc/zandopa-powder-otc237392 Restless leg syndrome with irritable bowel syndrome take cobadex czs once daily for 1 monthevion 400 mg once daily for 1 month Remedies for restless leg syndrome Ashwagandharishtam 15-15 ml twice a day with equal quantity of water For restless leg syndrome doctor? Tab pramirol 0.25 mg in evening daily Restless leg syndrome. Foot fingers pain Take massage with dhanwantaram oil, and then hot fomentation with medicated steam of Dashmool restless leg syndrome urgue move leg in night start tab pramirol 0.25 mg at nite Restless leg syndrome what is the cure Tab pramiro 0.25 mg Hs I am suffering from lack of proper sleep during the night for the last 20 days. Nights I am also suffering from cramps in lower legs when ever I have sleeping problem. Pl suggest remidy Hello, Welcome to 1mg. I am Anshul Varshney for your help. You have Restless leg syndrome. Get your iron profile, calcium levels , thyroid profile done.