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At a glance

Crotamiton + Permethrin is an antipruritic and scabicide medicine used for the treatment of scabies and relief of itching and skin irritation.

Indications
  • Scabies
  • Pruritus (itching)
  • Skin irritation (sunburn, dry eczema, itchy dermatitis, allergic rashes, hives, insect bites, heat rashes)
Pharmacology

Permethrin is a photostable synthetic pyrethroid that possesses a broad spectrum of insecticidal activity and low mammalian toxicity. Crotamiton is used to treat scabies infection and is also used to relieve the itching of certain skin conditions. Permethrin is rapidly absorbed by insects via mouth, respiratory tract or the intact cuticle. Although the primary target tissue is the nervous system, insects are not killed by dysfunction of a single organ but by a complex series of reactions in various organs, such as metabolic exhaustion and paralysis of the nervous system. Permethrin primarily affects sodium channels in the nerve membrane and causes prolongation of the transient increase in sodium permeability associated with membrane depolarization.

Dosage

Adult Dose: Apply once. If necessary, a second application may be given not less than 7 days after the initial application.

Pediatric Dose (2 months-2 years): Apply over whole body under doctor supervision.

Treatment Duration: Usually apply daily in the evening for 3-5 days.

Side effects

Common Side Effects:

  • Burning, stinging or tingling sensation
  • Erythematous rash
  • Itching
  • Dry skin
  • Paresthesia
Use in pregnancy

[CONSULT YOUR DOCTOR] Crotamiton + Permethrin may be unsafe to use during pregnancy, especially during the first three months.

Precautions & warnings
  • For external use only. Avoid contact with eyes.
  • Scabies is highly contagious; other family members should also use it preventively.
  • Not recommended during the first three months of pregnancy.
  • Nursing mothers should avoid applying it in the area of the nipples.
  • Corticosteroid treatment should be withheld prior to treatment with Permethrin and Crotamiton lotion (risk of exacerbating scabies infestation by reducing immune response to the mite).
Overdose effects

There are no reports of overdosage with Permethrin and Crotamiton lotion. Excessive application might result in localized adverse reactions or more severe skin reactions.

Storage conditions

Keep out of reach of children. Store in a dry place, below 25°C temperature and protected from light.

Crotamiton + Permethrin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.