osudhkosh

Piozena Plus 500

Rx
Dosage form:
Tablet
Pack size:
Tablet
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৳ 10/unit

Pack: ৳ 10

Price comparison

This brand
10
Cheapest of this genericActomeg 500
9

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At a glance

Metformin Hydrochloride + Pioglitazone is a combination medicine used to improve glycemic control in type 2 diabetes mellitus. Metformin reduces glucose production and absorption, and Pioglitazone increases insulin sensitivity.

Indications
  • Type 2 diabetes mellitus - as an adjunct to diet and exercise to improve glycemic control (when combination of pioglitazone and metformin is appropriate)
Dosage

Adult Dose (Oral):

  • Initial: 15/500 mg twice daily OR 15/850 mg once daily (with meals)
  • Switching from metformin monotherapy: 15/500 mg twice daily OR 15/850 mg 1-2 times daily
  • Switching from pioglitazone monotherapy: 15/500 mg twice daily OR 15/850 mg once daily
  • Maximum: Pioglitazone 45 mg + Metformin 2,550 mg/day
Side effects

Common Side Effects:

  • Nausea
  • Loss of appetite
  • Taste change
  • Abdominal pain
  • Diarrhea
  • Edema (peripheral edema)
  • Weight gain
  • Respiratory tract infection
  • Bone fracture
  • Blurred vision
Precautions & warnings
  • Inform doctor if symptoms of lactic acidosis occur (deep/rapid breathing, persistent nausea, vomiting, abdominal pain)
  • Monitor blood sugar regularly to avoid hypoglycemia
  • Avoid alcohol
  • Monitor liver function regularly (do not initiate if ALT >2.5x ULN)
  • Caution in history of heart failure or bladder cancer
Metformin Hydrochloride + Pioglitazone — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.