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Company•Synovia Pharma PLC.

Pneumo-23

0.5mlRx
Generic: Pneumococcal polysaccharide unconjugated Vaccine

৳ 1,926.88/unit

Pack: ৳ 1,926.88

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At a glance

Pneumococcal polysaccharide unconjugated Vaccine (23-valent) is used for prevention of pneumococcal disease in persons aged 2 years or older, especially those at high risk such as those with sickle cell disease, HIV infection, or other immunocompromising conditions.

Indications
  • Prevention of pneumococcal disease (in persons aged 2 years or older at high risk)
Pharmacology

The vaccine is prepared from 23 pneumococcal capsular polysaccharide serotypes: 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, 33F. It stimulates active immune response against S. pneumoniae capsular antigens, producing endogenous antibodies.

Dosage

Adults and Children (>2 years):

  • High-risk patients: Single dose of 0.5 mL (IM) as 23-valent vaccine
  • Should be given at least 2 weeks before elective splenectomy, chemotherapy, or immunosuppressive treatment
  • Revaccination generally not required; may be considered after 5 years in patients with asplenia, splenic dysfunction, or nephrotic syndrome
Side effects

Common Side Effects:

  • Injection site pain, erythema (redness), induration, and edema
  • Moderate and transient hyperthermia (fever) sometimes >39°C
  • Adenopathy, rashes, arthralgia
  • Allergic reactions (urticaria, Quincke's edema, anaphylactoid reactions)
  • Headache, muscle pain, malaise, fatigue (rare)
Use in pregnancy

Use in Pregnancy: Information regarding use during pregnancy is not available; consult your doctor.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in severe renal, hepatic, cardiac, vascular &/or pulmonary dysfunction
  • Patients on immunosuppressants may be unable to attain required antibody titres
  • Caution in pregnancy and lactation
  • Efficacy may be reduced in multiple myeloma, Hodgkin's and non-Hodgkin's lymphoma (especially during treatment and chronic alcoholism)
  • Vaccine should be given 2 weeks before starting immunosuppressive treatment or at least 3 months after treatment completion
Overdose effects

No overdose information available; consult your doctor if overused.

Storage conditions

Store refrigerated at 2-8°C; protect from light.

Pneumococcal polysaccharide unconjugated Vaccine — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.