৳ 2.41/unit
Pack: ৳ 2.41
৳ 2.41/unit
Pack: ৳ 2.41
At a glance
Carbonyl Iron + Folic Acid is a combination capsule used for the treatment of iron deficiency anemia, megaloblastic anemias due to folic acid deficiency, and nutritional anemias. Carbonyl iron has high bioavailability and low toxicity, and folic acid supports nucleoprotein synthesis.
Indications
- Iron deficiency anemia
- Megaloblastic anemias due to folic acid deficiency
- Anemias of nutritional origin
- Pregnancy anemia
- Infancy or childhood anemia
Pharmacology
Iron replaces iron stores found in hemoglobin, myoglobin, and enzymes, and works to transport oxygen via hemoglobin. Folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase, which is required for nucleoprotein synthesis.
Dosage
Adults: One capsule daily before food. In more severe cases, 2 capsules a day may be required, or as directed by the physician.
Pregnancy: May be used during the second and third trimesters under medical supervision.
Note: For maximum absorption, take on an empty stomach; may take with or after meals to minimize GI irritation.
Side effects
Iron (>10%): Constipation, diarrhea, nausea, epigastric pain, dark stools, vomiting.
Frequency Not Defined: Hemosiderosis (during long-term administration of large amounts), urine discoloration, dental stain by some formulations, heartburn.
Folic acid: Bronchospasm, erythema, malaise, pruritus, rash, slight flushing, allergic sensitization.
Oral iron preparations may cause constipation, particularly in older patients, occasionally leading to fecal impaction.
Use in pregnancy
Avoid use during the first trimester of pregnancy if possible; may be used during the second and third trimesters under medical supervision (1 capsule daily).
Precautions & warnings
- Caution in patients who may develop iron overload (hemochromatosis, hemolytic anemia, red cell aplasia).
- Iron chelates with tetracycline, impairing absorption; maintain at least 2-3 hours gap.
- Antacids decrease iron absorption; maintain at least 2 hours gap.
- Avoid use during the first trimester of pregnancy if possible; use during second and third trimesters under medical supervision.
- Safe during lactation; excreted in breast milk.
Overdose effects
Overdose may cause iron toxicity (vomiting, diarrhea, abdominal pain, shock, coma) and folic acid overdose symptoms. Consult your doctor immediately if overdose is suspected.
Storage conditions
Do not store above 30°C. Keep away from light and moisture. Keep out of reach of children.