Premarin0.625mg

• Hormone Replacement Therapy: Used for menopause symptoms such as hot flushes, night sweats and vaginal dryness.
• Osteoporosis Prevention: Used for prevention of bone loss and fractures in postmenopausal women.
• Prostate Cancer: Used for palliative treatment.
• Breast Cancer: Used for palliative treatment in selected metastatic patients.

Adult Dose (Oral):

• Menopausal Vasomotor Symptoms, Atrophic Vaginitis: 0.3 mg PO once daily (continuous or cyclic regimen)
• Female Hypogonadism: 0.3-0.625 mg PO once daily (cyclic: 3 weeks on, 1 week off)
• Osteoporosis Prophylaxis: 0.3 mg PO once daily (cyclic: 25 days on, 5 days off)
• Prostate Cancer (Palliative): 1.25-2.5 mg PO q8hr
• Abnormal Uterine Bleeding: 10-20 mg/day PO divided q4hr
• Breast Cancer (Palliative): 10 mg PO q8hr for >=3 months

Common Side Effects:

• Bloating
• Breast pain
• Hair loss
• Headache
• Irregular vaginal bleeding
• Nausea
• Stomach cramp
• Vomiting

Precautions:

• It is not known whether Estrogens alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
• Prescribed as part of HRT to relieve symptoms of menopause.
• Take at the same time every day.
• Inform your doctor if you experience any unusual vaginal bleeding, discharge or vaginal discomfort.
• May increase risk of breast cancer; have regular breast examinations.
• Stop taking and inform doctor immediately if unexplained swelling and pain in limbs, shortness of breath, chest pain, or changes in vision occur.