osudhkosh
New
Company•Renata Limited

Protogyn

500mgRx
Generic: Tinidazole

৳ 4/unit

Pack: ৳ 4

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At a glance

Tinidazole is a 5-nitroimidazole antibiotic and antiprotozoal used for bacterial and parasitic infections. It eliminates infections by damaging the DNA of microorganisms.

Indications
  • Bacterial vaginosis
  • Anaerobic bacterial infections
  • Prophylaxis of postoperative anaerobic infections
  • H. pylori eradication (in peptic ulcer)
  • Intestinal amoebiasis, hepatic amoebiasis
  • Giardiasis
  • Trichomoniasis
  • Acute necrotising ulcerative gingivitis
Pharmacology

Tinidazole enters microorganisms and is reduced by ferredoxin, producing active intermediate compounds that damage DNA strands or inhibit DNA synthesis, causing microorganism death.

Dosage

Adult Dose (Oral):

  • Bacterial vaginosis: 2 g single dose (or 2 g for 2 days, or 1 g/day for 5 days)
  • Anaerobic infections: 2 g on day 1, then 1 g/day or 500 mg twice daily (5-6 days)
  • Postoperative prophylaxis: 2 g single dose (12 hours before surgery)
  • H. pylori: 500 mg twice daily (with clarithromycin and omeprazole for 7 days)
  • Intestinal amoebiasis: 2 g/day (2-3 days)
  • Hepatic amoebiasis: 1.5-2 g/day (3-6 days)
  • Giardiasis/Trichomoniasis: 2 g single dose

Pediatric Dose (Oral):

  • Intestinal amoebiasis (>3 years): 50-60 mg/kg/day (3 days); max 2 g/day
  • Hepatic amoebiasis (>3 years): 50-60 mg/kg/day (5 days); max 2 g/day
  • Giardiasis (>3 years): 50-75 mg/kg single dose; max 2 g/day
Side effects

Common Side Effects:

  • Headache
  • Dry mouth
  • Nausea
  • Metallic taste
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies show harmful effects; do not use in the 1st trimester; consult your doctor.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Do not consume alcohol (disulfiram-like reaction)
  • Do not use in blood dyscrasias, organic neurologic disorders
  • Do not use in the 1st trimester of pregnancy
  • High doses or prolonged use increase risk of nerve damage
Overdose effects

No overdose information available; excessive doses may increase side effects; consult your doctor.

Storage conditions

Store in a cool and dry place, protected from light; keep out of reach of children.

Tinidazole — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.