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At a glance

Racecadotril is used for the treatment of symptoms of acute diarrhea. It is an anti-secretory agent that reduces the secretion of water and electrolytes from the intestine, helping to reduce fluid loss from the body in diarrhea.

Indications
  • Acute diarrhea
Pharmacology

Racecadotril increases enkephalin levels in the gut by inhibiting enkephalinase enzyme. Enkephalins activate delta-opioid receptors, which reduce cAMP levels in intestinal cells and decrease water and electrolyte secretion, thereby reducing diarrhea.

Dosage

Adult Dose (Oral):

  • Acute diarrhea: 100 mg three times daily
  • Continue until 2 normal stools are recorded; max duration 7 days

Pediatric Dose (Oral):

  • 3 months-17 years 27 kg: 60 mg three times daily
  • Continue until 2 normal stools are recorded; max duration 7 days
Side effects

Common Side Effects:

  • Vomiting
  • Fever
Use in pregnancy

Use in Pregnancy: Information regarding use during pregnancy is not available; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Does not usually affect driving ability
  • Use with oral rehydration solution (ORS)
  • Do not use if blood and pus in stools or fever (may be bacterial infection)
  • Do not use in uncontrolled vomiting
  • Do not use in children under 3 months
  • Do not take for more than 7 days
Overdose effects

No overdose information available; consult your doctor if taken in excess.

Storage conditions

Store in a cool and dry place; keep out of reach of children.

Racecadotril — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.