Ramelta8mg
Rx- Generic:
- Ramelteon
- Company:
- Incepta Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 35/unit
Pack: ৳ 35
At a glance
Ramelteon — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Ramelteon is a prescription medicine used in the treatment of insomnia. It helps to synchronize the body’s biological day-night rhythm. It resolves trouble falling asleep and ensures sound sleep. Unlike other medicines, it is not habit-forming. Ramelteon may be taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. You should never skip any doses and finish the full course of treatment even if you feel better. This medicine should not be stopped suddenly without talking to your doctor. Some common side effects of this medicine include fatigue and nausea. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to note that this medicine should not be used for daily naps. Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it. Ramelteon is a melatonin receptor agonist. Ramelteon works like melatonin, a chemical messenger in the brain that helps regulate the sleep-wake cycle.
Indications
• Insomnia
Mechanism of action
Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT1 and MT2 receptors and selectivity over the MT3 receptor. The activity of ramelteon at the MT1 and MT2 receptors is believed to contribute to its sleep-promoting properties, as these receptors, acted upon by endogenous melatonin, are thought to be involved in the maintenance of the circadian rhythm underlying the normal sleep-wake cycle.
Dosage
Adult Dose: Adult: Tablet 8 mg taken within 30 minutes of going to bed. Total daily dose should not exceed 8 mg. Child Dose: Safety and efficacy not established
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ramelteon may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Ramelteon, skip it and continue with your normal schedule. Do not double the dose.
Side effects
Common: • Dizziness • Sleepiness • Fatigue • Insomnia (difficulty in sleeping) • Nausea
Precautions & warnings
[UNSAFE] Ramelteon may cause side effects which could affect your ability to drive. You have been prescribed Ramelteon to treat difficulty in falling asleep. Take it without food at least 30 minutes before you sleep. It may cause increased sleepiness. Do not drive or do anything requiring mental focus until you know how it affects you. Avoid taking alcohol while taking this medicine as that may increase the side effects of this medicine. Consult with a doctor if your sleep doesn’t improve after 7 to 10 days of treatment. Inform your doctor if you notice behavioral changes or new or worsening depression while taking this medicine. Stop taking medication and inform your doctor If you experience sleep-driving or memory loss.
Contraindications
Hypersensitivity Ramelteon is not recommended in patients with severe hepatic impairment. Patients who develop angioedema after treatment with Ramelteon should not be re-challenged with the drug.
Drug interactions
Rifampin (strong CYP enzyme inducer): Decreases exposure to and effects of ramelteon. Ketoconazole (strong CYP3A4 inhibitor): Increases AUC for ramelteon; administer with caution. Fluconazole (strong CYP2C9 inhibitor): Increases systemic exposure of ramelteon; administer with caution. Donepezil increases systemic exposure of ramelteon; patients should be closely monitored when ramelteon is coadministered with donepezil. Doxepin increases systemic exposure of ramelteon; patients should be closely monitored when ramelteon is coadministered with doxepin. Alcohol: Causes additive psychomotor impairment; should not be used in combination.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Ramelteon.
Use in pregnancy
[CONSULT YOUR DOCTOR] Ramelteon may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Ramelteon is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Monitor the baby for sleepiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed babies.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Ramelteon is safe to use in patients with kidney disease. No dose adjustment of Ramelteon is recommended. [CAUTION] Ramelteon should be used with caution in patients with liver disease. Dose adjustment of Ramelteon may be needed. Please consult your doctor. Use of Ramelteon is not recommended in patients with severe liver disease.
Common questions
Want to take Ramitax for insomnia , venlor 300 per day taking, how effective it will be Response to medicines depends on- 1. Diagnosis 2. Adequate dose of medicines 3. Adequate duration of treatment 4. Regular Medicines 5. Individual factors like patient's metabolism, other medical conditions etc. I have disturbed stomach all the time my weight is also high i have breakfast in morning near about 12:30 and very little bit sleep no sound sleep very disturbed sleep with lots of sapne in nights i came from my chemist late in night and despite of so many work ididnt got sound sleep i take clonofit beta in night but no response suggested by doctor so plz advise best medicine from which i got sound sleep and fresh feel in morning Ramitax 8 mg at nite for 3 weeks I am suffering from insomnia Take zzowin tablet 2 tablet at night Insomnia, lack sleep and calmness Take zzowin tablet 2Tablet at night, brahmi vati 2 tablet twice Ayurvedic is good for insomnia people.i have insomnia https://www.1mg.com/otc/jiva-sleep-well-tablet-otc329958One ?one capsules morning & evening after taking food , use at least 1-2 months Insomnia,can I take Rilanx cap from atrimed,as it contains Jatamansi Take Tagar tablet 2 tablet twice Insomnia not getting proper sleep in night 1 year old problem. Take tagar tablet 2 tablet in night, add Brahm rasayan 1 spoon twice with water I suffer from insomnia for the last 20 years now l take half tablet of ZOLFRESH 5 mg tablet but get. a hangover next day so please suggest some better tablet for which l will be ever grateful Thanks PATIENT Take Zolfresh at the time of going to bed. It is a short acting drug and suitable for Insomnia for you. also follow the sleep hygiene