Rasalet 1

Rasagiline is a medicine used to treat Parkinson's disease. It helps to provide better control of body movements and prevents excessive shaking and stiffness. It increases the concentration of a chemical in the brain called dopamine that plays a major role in movement control. Rasagiline can be taken alone or in combination with other medicines. It may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. You should never skip any doses and try to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it can result in confusion, stiff muscles, and a high fever. Some common side effects of this medicine include joint pain, insomnia (difficulty sleeping), dyspepsia (indigestion), influenza or cold like symptoms, depression, cough and peripheral edema (swelling in the extremities, especially lower limbs). It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. You should undergo periodic examinations to detect skin cancer while taking this medicine as it increases the risk of developing cancer. Inform your doctor if you develop any unusual changes in mood, hallucinations, an abnormally high sex drive, an urge to gamble or uncontrolled spending as these may prove very harmful. Rasagiline works by increasing the amount of dopamine, a chemical messenger that is needed to control movement in the brain.

• Parkinson's disease

Rasagiline is a potent, irreversible monoamine oxidase (MAO)-B selective inhibitor which may cause an increase in extracellular levels of dopamine in the striatum, leading to reduced symptomatic motor deficits of Parkinson's disease.

Adult Dose: Parkinson Disease Monotherapy: 1 mg PO qDay Adjunct without levodopa: 1 mg PO qDay Adjunct to levodopa: 0.5 mg PO qDay initially, may increase to 1 mg/day if needed and tolerated; consider reducing levodopa dose Hepatic impairment Mild (Child-Pugh A): Not to exceed 0.5 mg/day Moderate-to-severe (Child-Pugh B/C): Do not use Child Dose: <18 years: Safety and efficacy not established Renal Dose: Renal impairment: No dosage adjustment required for mild-to-moderate; not studied in severe

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rasagiline may be taken with or without food, but it is better to take it at a fixed time.

Common: • Joint pain • Insomnia (difficulty in sleeping) • Indigestion • Flu-like symptoms • Depression • Cough • Peripheral edema

[UNSAFE] Rasagiline may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Rasagiline to treat your symptoms of Parkinson's disease. It can be taken with or without food or as directed by your doctor. Be cautious while driving or doing anything that requires concentration as Rasagiline can make you very sleepy. Rasagiline can make you dizzy or lightheaded, especially when you suddenly stand up from sitting or laying down. Let your doctor know if you are also taking medicines for depression or mood disorders. Do not stop taking Rasagiline suddenly. Sudden stopping may cause confusion, stiff muscles and a high fever. As a precaution, foods high in tyramine (e.g. aged cheeses, air-dried meat, soy sauce, tap/draft beers and red wine) should be avoided when taking Rasagiline, as it may cause an unsafe rise in your blood pressure.

Severe hepatic impairment. Concomitant use w/ other MAOIs and pethidine w/in 14 days after discontinuation of therapy; St John's wort.

Increased plasma levels w/ potent CYP1A2 inhibitors (e.g. ciprofloxacin). Increased clearance w/ entacapone. Potentially Fatal: Increased risk of non-selective MAO inhibition w/ other MAOIs and pethidine that may lead to hypertensive crises.

[UNSAFE] It is unsafe to consume alcohol with Rasagiline.

[CONSULT YOUR DOCTOR] Rasagiline may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Rasagiline is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Rasagiline is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rasagiline may not be needed in these patients. Please consult your doctor. [CAUTION] Rasagiline should be used with caution in patients with liver disease. Dose adjustment of Rasagiline may be needed. Please consult your doctor. Use of Rasagiline is not recommended in patients with moderate and severe liver disease.

I am diagnosed as Parkinson&#x27;s disease.continuing syndoppa plus,rasalect,pacitane but now weight is reducing and feeling week.digestion is not Proper sometimes suffering from loose motion,and no appetite Pls show 2 physician Parkinson&#x27;s disease tremors ,Insomnia. Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months My father is suffering from Parkinson&#x27;s from last 8 years he is currently taking syndopa n rasalect. But after taking medicine he feels better but post 2 hours he feels dizzy n starts to loose control on his body. Any alternate medicine u suggest pls get exmaioned for proper assesment by neuro de My mother suffering from Parkinson disease from 7 year , any affective medicine ?? Both hand and leg is shaking ,hardly stand up from bed himself, using parking tablet, syndopa plus and parkitidin Dear sir Parkinson&#x27;s can only be managed with Homeopathy. There are few medicines which are used to improve quality of life and decrease disease progression Parkinson&#x27;s disease for 25 yrs. Taking allopathy Suggestions needed Kindly consult to any good Ayuvedic Panchkarma center. Panchkarma therapy will give you some result . I am suffering from neck pain last month and I am also a patient of Parkinson&#x27;s disease and I am taking syndopa plus and pacitane last 1 year but not feeling well please tell me advise please sir thanks try tab tolfree 150 mg bd for a week Parkinson&#x27;s disease treatment difficulty in movement My father&#x27;s age is 59 .He is suffering from vascular perkinson.suggest me diet and medicine Kappikachu churan half spoon twice with milk, Ashwgandha churan 1 spoon twice with milk Hi my mom had Parkinson&#x27;s disease but didn&#x27;t get any operation but using tablets syndopa last night she take another tablet of pain killer with it by the morning my mom to full shivering of hands and legs so what do u suggest to do? need to examine to opine