Rasilez300mg

Aliskiren is a medicine used in the treatment of high blood pressure (hypertension). It lowers blood pressure by helping in relaxing blood vessels. Lowering the blood pressure helps to prevent future heart attack and stroke. Aliskiren should be taken regularly as advised by the doctor. You should take it with or without food and at a fixed time. You should never stop it abruptly without consulting the doctor. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This may lead to your blood pressure rising up again and increase your risk of heart disease and stroke. It is important to have your blood pressure checked regularly. This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake and weight reduction. You can eat normally while taking this medicine, but try to reduce your salt intake. It may cause side effects like diarrhea, dizziness, and joint pain. This medicine may not be suitable for some people. You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it. Aliskiren is a direct renin inhibitor. It works by relaxing blood vessels which lower blood pressure and allows the heart to pump more efficiently.

• Hypertension (high blood pressure)

Administration May be taken with or without food. Take consistently w/ or w/o meals. Avoid taking w/ high fat meals.

Adult Dose: Serious CHF, sodium or volume depletion. Discontinue if diarrhoea is severe and persistent. Lactation. Monitoring Parameters Periodically monitor serum potassium concentration and renal function. Discontinue as soon as possible when pregnancy is detected; affects renin-angiotensin system causing oligohydramnios, which may result in fetal injury and/or death. Lactation: Excretion in milk unknown/not recommended. Child Dose: C (1st trimester), D (2nd & 3rd trimesters) Renal Dose: Aliskiren is an orally active, potent, non-peptide and selective direct renin inhibitor used in the management of HTN. By inhibiting the enzyme renin, it prevents conversion of angiotensinogen into angiotensin I and therefore inhibits subsequent production of angiotensin II and aldosterone. Unlike ACE inhibitors and angiotensin II receptor antagonists which cause a compensatory rise in plasma renin activity, treatment w/ aliskiren decreases plasma renin activity and concentrations of angiotensin I, angiotensin II and aldosterone .

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aliskiren may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Aliskiren, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Diarrhea • Dizziness • Joint pain • Increased potassium level in blood

[UNSAFE] Aliskiren may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. For better results, take it at the same time every day. It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. Avoid alcohol while taking Rasilez 150mg Tablet FC as it may increase dizziness. Notify your doctor if you have rapid swelling of the lips, tongue, and throat that may cause breathing problem. Notify your doctor if you have any kidney problem. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

History of angioedema; severe renal impairment. Concomitant use w/ ACE inhibitors or angiotensin II receptor antagonists in patients w/ DM and renal impairment (GFR <60 mL/min). Concomitant use w/ ciclosporin, itraconazole and quinidine. Pregnancy.

[UNSAFE] Aliskiren may cause excessive drowsiness with alcohol.

[CONSULT YOUR DOCTOR] Aliskiren is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[SAFE IF PRESCRIBED] Aliskiren is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Aliskiren should be used with caution in patients with kidney disease. Dose adjustment of Aliskiren may be needed. Please consult your doctor. Limited information is available on the use of Aliskiren in these patients. Regular monitoring of creatinine and potassium levels is recommended while you are taking this medicine. [CAUTION] Aliskiren should be used with caution in patients with severe liver disease. Dose adjustment of Aliskiren may be needed. Please consult your doctor. Limited information is available on the use of Aliskiren in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

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