rFSH 75 IU
75IU/vialRx৳ 1,900/unit
Pack: ৳ 1,900
৳ 1,900/unit
Pack: ৳ 1,900
At a glance
Recombinant Follicle Stimulating Hormone (rFSH) is used for ovarian follicle stimulation in women and spermatogenesis in men. It is used in infertility treatment to induce ovarian hyperstimulation and spermatogenesis.
Indications
- Ovarian follicle stimulation in women (superovulation)
- Spermatogenesis induction in men
- Infertility treatment (IVF, ICSI)
Pharmacology
Recombinant FSH stimulates ovarian follicle growth and maturation and spermatogenesis, similar to natural FSH. It binds to FSH receptors, activating adenylate cyclase and increasing cAMP production, leading to follicle growth and estrogen secretion.
Dosage
Adult Dose (SC/IM):
- Female (superovulation): Start on cycle day 2-3, 75-300 IU/day, adjust dose based on hormonal response
- Male (spermatogenesis): 75-150 IU 2-3 times weekly for at least 3-6 months
- Dose individualization required; as directed by physician
Side effects
Side Effects:
- Ovarian Hyperstimulation Syndrome (OHSS)
- Multiple pregnancy
- Injection site reactions
- Abdominal pain
- Nausea
- Headache
- Mood swings
Use in pregnancy
Use in Pregnancy: Not safe during pregnancy; do not use.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Risk of Ovarian Hyperstimulation Syndrome; monitor ovarian size and estrogen levels
- Risk of multiple pregnancy
- Do not use in pregnancy, lactation, ovarian cysts, unexplained vaginal bleeding, pituitary tumors
Overdose effects
Overdose: Risk of Ovarian Hyperstimulation Syndrome; treatment: symptomatic supportive care, monitoring.
Storage conditions
Store at 2-8°C in the refrigerator; protect from light; do not freeze.