Rheumet25mg
Rx- Generic:
- Indomethacin
- Company:
- Pharmadesh Laboratories Ltd.
- Dosage form:
- Capsule
- Pack size:
- Capsule
৳ 0.62/unit
Pack: ৳ 0.62
At a glance
Indomethacin — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Indomethacin helps in relieving moderate pain and reducing fever. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis, osteoarthritis, gout and ankylosing spondylitis. Indomethacin should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke. Vomiting, stomach pain, nausea and indigestion are some of the common side effects that might be observed on taking this medicine. It may also cause dizziness, drowsiness or visual disturbances. Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment. Long term use may lead to serious complications such as stomach bleeding and kidney problems. Indomethacin is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
Indications
• Pain relief
Mechanism of action
Indometacin, an indole acetic acid derivative has anti-inflammatory, analgesic and antipyretic actions. It reversibly inhibits cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, thus resulting in reduced synthesis of prostaglandin precursors.
Dosage
Adult Dose: Oral Inflammatory/Rheumatoid Disorders Immediate release: 25-50 mg PO q8-12hr; not to exceed 200 mg/day Extended release: 75-150 mg/day PO in single daily dose or divided q12hr; not to exceed 150 mg/day Bursitis/Tendinitis Immediate-release: 75-150 mg/day PO divided q6-8hr Extended-release: 75-150 mg/day PO in single daily dose or divided q12hr Acute Gouty Arthritis 50 mg PO q8hr for 3-5 days; reduced once pain is under control Rectal Pain and inflammation associated with musculoskeletal and joint disorders Adult: As supp: 100 mg to be inserted at night and repeated in the morning if necessary. Child Dose: Inflammatory/Rheumatoid Disorders 14 years: 25-50 mg IR PO q8-12hr; not to exceed 200 mg/day; 75-150 mg/day ER PO in single daily dose or divided q12hr; not to exceed 150 mg/day
Administration
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Indomethacin is to be taken with food.
Side effects
Common: • Vomiting • Stomach pain/epigastric pain • Nausea • Indigestion • Diarrhea • Heartburn • Loss of appetite
Precautions & warnings
[UNSAFE] Indomethacin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Indomethacin to relieve pain and inflammation. Take it with food or milk to prevent upset stomach. Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems. It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration. Avoid consuming alcohol while taking Indomethacin as it can cause excessive drowsiness and increase your risk of stomach problems. Inform your doctor if you have a history of heart disease or stroke. Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.
Contraindications
Indomethacin is contraindicated in patients with ulcer, gastritis, active ulcerative colitis, and should be used with caution in patients with a history of these disorders. It is also contraindicated in previously hypersensitive patient.
Drug interactions
May increase plasma levels of methotrexate. Increased risk of GI bleeding w/ warfarin. May reduce hypotensive effects of hydralazine, furosemide, ?-blockers (e.g. atenolol, propranolol, oxprenolol), or thiazide diuretics. Increased risk of hyperkalaemia w/ K-sparing diuretics, ACE inhibitors, K supplements. May increase nephrotoxic effects of ciclosporin or triamterene. Increase plasma concentration w/ probenecid. May increase plasma levels of aminoglycoside (e.g. amikacin, gentamicin) in premature neonates. May enhance antipsychotic effect (e.g. severe drowsiness and confusion) of haloperidol. Al- or Mg-containing antacids may reduce GI disorders of indometacin. Potentially Fatal: Diflunisal decreases renal clearance and increases plasma concentrations of indometacin which leads to fatal GI haemorrhage.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Indomethacin.
Use in pregnancy
[CONSULT YOUR DOCTOR] Indomethacin is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Indomethacin is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Indomethacin is safe to use in patients with kidney disease. No dose adjustment of Indomethacin is recommended. However, a regular monitoring of kidney function test and potassium levels is advised while you are taking this medicine. Please consult your doctor. [CAUTION] Indomethacin should be used with caution in patients with liver disease. Dose adjustment of Indomethacin may be needed. Please consult your doctor.
Common questions
Arthritis and joint swelling /pain continues HB is 9 Medicine INDOCAP SR.1/night ATEN AM & ciladuo Not feeling well. Regularly take INDOCAP SR at 1/night Please do following investigations RA factor, ESR, CRP, |S-URIC ACID levels and Vitamin-D levels Pain and stiffness in joints and back bone pain please do following investigation RA factor, ESR, CRP, S.Uric acidTill then Take Tab Indocap-SR twice daily I have pain in all joints in morning Kya karoon? Initial Medical Mn C Indocap SR 75 mg twice daily, T Aciloc 150 mg twice daily for a weekIf no relief may need additional T Deflazacort 12 mg twice daily and lab tests Facing pain in knee joint n interphalangeal joints Swelling at right wrist Do following investigations RA factor, ESR, CRP, S. Uric acidTill then take Tab Indocap-SR and Tab Chymoral forte twice daily for 3 days Early morning suffer from Hand back and leg pain. All muscles gets tighten that I couldn't walk and feels powerless. As day progresses feels normal. Please guide as I m clueless. Do following investigations RA factor, S.Uric acid, ESR, CRP and showTill then Take Tab Indocap-SR and Tab Flotrip-forte twice daily Sir i have 1 yaer joint pain docter suggest folitrax2.5mg tab i take this tablet but no result.sir this tablet to be continue or no which side effect of this tablet plz tell me. Please get the following blood investigations doneRA factor, ESR, CRP, S.Uric acidTake Tab Indocap-SR twice daily for next 3 days. I have joint pain , whole joint in my body get pain mostly back bone. knee pain comes while driving give some remedies for my pains and most suitable medicine too Do following investigations RA factor, ESR, CRP, S.Uric acidApply Dynapar QPS spray over the affected joints and take Tab Indocap-SR and Tab Flotrip-forte twice daily Joint pain in my foot from 2 month Do following investigations S.uric acid, ESR, CRPTill then take Tab Indocap-SR twice daily and Tab Flotrip-forte thrice daoly for 5 daysApply Dynapar QPS spray locally over the affected area