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At a glance

Oxymetazoline Hydrochloride topical cream is used for the treatment of persistent facial erythema associated with rosacea in adults. It acts as a vasoconstrictor of the cutaneous microvasculature.

Indications
  • Topical treatment of persistent facial erythema associated with rosacea in adults
Pharmacology

Oxymetazoline acts as an α1A adrenoreceptor agonist to constrict blood vessels in the cutaneous microvasculature, reducing facial redness associated with rosacea.

Dosage

Adult Dose (Topical):

  • Apply a pea-sized amount once daily in a thin layer to entire face (forehead, nose, cheeks, chin)
  • Avoid eyes and lips
Side effects

Common Side Effects (1-10%):

  • Application-site dermatitis (2%)
  • Worsening inflammatory lesions of rosacea (1%)
  • Application-site pruritus (1%)
  • Application-site erythema (1%)
  • Application-site pain (1%)
Use in pregnancy

Use in Pregnancy: No data on topical oxymetazoline use in pregnant women; potential association between second-trimester exposure and renal collecting system anomalies identified.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • α-Adrenergic agonists may impact blood pressure; caution in cardiovascular disease, orthostatic hypotension, uncontrolled hypertension/hypotension
  • Caution in cerebral/coronary insufficiency, Raynaud's phenomenon, thromboangiitis obliterans, scleroderma, Sjogren's syndrome
  • Seek immediate medical care if signs of acute narrow-angle glaucoma develop
Overdose effects

Overdose unlikely (topical use); symptomatic treatment.

Storage conditions

Store at room temperature; protect from excessive heat; keep out of reach of children.

Oxymetazoline Hydrochloride topical — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.