৳ 1,548.50/unit
Pack: ৳ 1,548.50
৳ 1,548.50/unit
Pack: ৳ 1,548.50
At a glance
Rotavirus Live Attenuated Oral Vaccine is used to prevent rotavirus gastroenteritis in infants and young children. It is administered orally in 2 doses starting from 6 weeks of age, with the second dose given after at least 4 weeks and before 24 weeks of age.
Indications
- Prevention of rotavirus gastroenteritis
Pharmacology
Rotavirus vaccine viruses replicate in the small intestine and stimulate active immunity. The monovalent vaccine derived from human strain prevents rotavirus gastroenteritis caused by G1, G3, G4, G9 serotypes, while the pentavalent vaccine prevents disease caused by G1, G2, G3, G4 serotypes.
Dosage
Pediatric Dose (Oral):
- 2-Dose Regimen: Total of two 1 ml doses administered orally
- First dose: Starting at 6 weeks of age
- Second dose: At least 4 weeks after the first dose and before 24 weeks of age
Side effects
Common Side Effects (>10%):
- Diarrhea (24.1%)
- Vomiting (15.2%)
- Otitis media (14.5%)
- Fever (17-43%)
- Fussiness/irritability (3-52%)
1-10%:
- Nasopharyngitis (6.9%)
- Bronchospasm (1.1%)
- Flatulence (2%)
Use in pregnancy
Use in Pregnancy: Not applicable; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in history of chronic GI disorders, chronic diarrhea, congenital abdominal disorders, abdominal surgery
- Defer vaccination in acute diarrhea, vomiting, or severe febrile illness
- Monitor for signs of intussusception (severe abdominal pain, persistent vomiting, bloating, blood in stools, high fever)
- Monitor for Kawasaki disease symptoms (fever, rash, red eyes, red mouth, swollen hands/feet)
- Caution with non-vaccinated or immunodeficient contacts
Overdose effects
No overdose information available; consult your doctor.
Storage conditions
Store in a refrigerator at 2-8°C; protect from light; keep out of reach of children.