oshudhkosh

Rozy Ds0.50mg+1.00mg

OTC
Dosage form:
Tablet
Pack size:
Box (15 Tablet)

৳ 24/unit

Pack: ৳ 360

At a glance

Drospirenone + Estradiol — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Drospirenone + Estradiol is a combination of two medicines used for contraception (to prevent pregnancy) and in the treatment of irregular periods. It helps to prevent release and fertilization of the egg. Drospirenone + Estradiol can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. You should have to start taking the pill on the day one of your menstrual cycle and continue taking it for whole month and start with new pack once the pack get finished. If you experience vomiting with in 4 hours of dose intake, take another tablet. You body may take 7 days to get adjust with medicine, hence use condom during first week to avoid pregnancy. In case you missed your dose and you are late by 12 hours in taking the missed dose, in that case must use a condom while intercourse for a period of 2 days. Nausea, headache, breast pain, and weight gain are some commonly seen side effects of this medicine. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them. You might experience spotting or bleeding between menstrual periods or missed periods. Consult with your doctor if this occurs frequently or persists longer. Inform your doctor if you notice swelling and pain in your limbs, shortness of breath, chest pain or changes in vision, as it may be a sign of blood clot. Before taking this medicine, let your doctor know if you smoke and are over 35, or if you have ever had a heart attack or have cancer of uterus/cervix, or vagina. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Do not take the medicine if you are pregnant already or breastfeeding. You might be asked for regular check-up of blood pressure, cholesterol and blood sugar level while on treatment. Drospirenone + Estradiol is a combined oral contraceptive pill. It works by preventing the release of egg (ovulation) and affecting sperm movement in the womb to prevent its union with the egg. It also changes the lining of the womb and renders it unsuitable for pregnancy.

Indications

• Contraception

Mechanism of action

Estradiol: Endogenous estrogen; reduces the release of gonadotropin-releasing hormone from hypothalamus, reduces release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from pituitary gland; increases synthesis of DNA, RNA, and various proteins in target tissues. Estrogen replacement reduces elevated levels of estrogen and progesterone LH and FSH in postmenopausal women Drospirenone: Progestin; spironolactone analog with antimineralocorticoid and antiandrogenic activity

Dosage

Adult Dose: Hormone Replacement Therapy Oral Tablet 1 tablet PO daily Hepatic impairment In women with mild or moderate hepatic impairment, DRSP is well tolerated. It is contraindicated in women with severe hepatic disease Renal Dose: Renal Impairment In women with mild or moderate renal impairment, a slight increase of Drug Resistant Streptococcus Pneumoniae exposure was observed but is not expected to be of clinical relevance. It is contraindicated in women with severe renal disease.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Drospirenone + Estradiol may be taken with or without food, but it is better to take it at a fixed time.

Side effects

Common: • Nausea • Stomach pain • Headache • Weight gain • Breast pain • Irregular uterine bleeding

Precautions & warnings

[SAFE] Drospirenone + Estradiol does not usually affect your ability to drive. Your doctor has prescribed Drospirenone + Estradiol to help you prevent pregnancy. It also results in lighter, less painful and more regular menstrual bleeding. It may help reduce the risk of ovarian cancer. Take your pill at the same time every day to help you remember to take it. You may experience menstrual irregularities such as spotting or bleeding between menstrual periods or missed periods. Consult your doctor if this persists. Do not use Drospirenone + Estradiol if you are obese, over 35, smoke, on prolonged bed rest, or have a history of blood clots. Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein. Stop taking Drospirenone + Estradiol and inform your doctor immediately if you notice your skin and whites of the eye turning yellow (jaundice), severe stomach pain, severe depression or if you think you could be pregnant.

Contraindications

Hormone replacement therapy (HRT) should not be started in the presence of any of the conditions listed below. The product should be stopped immediately, if any of the conditions appear during HRT use. Undiagnosed abnormal genital bleeding Known or suspected cancer of the breast Known or suspected premalignant conditions or malignancies, if sex steroid-influenced The excess risk disappears within a few years after stopping HRT. Endometrial cancer Prolonged exposure to unopposed estrogens increases the risk of development of endometrial hyperplasia or carcinoma. The addition of DRSP opposes the development of endometrial hyperplasia caused by estrogens. Liver tumors In rare cases benign, and even more rarely, malignant liver tumors have been observed after the use of hormonal substances such as those contained in HRT products. In isolated cases, these tumors led to life-threatening intra-abdominal hemorrhage.

Drug interactions

Pharmacodynamic interaction with antihypertensive medications and non-steroidal anti-inflammatory drugs (NSAID) Hypertensive women treated with this combination drugs and anti-hypertensive medications, e.g. ACE inhibitors, angiotensin II receptor antagonists, and hydrochlorothiazide may experience an additional decrease in blood pressure. Combined use of this and NSAIDs or antihypertensive medications is unlikely to increase serum potassium. Concomitant use of these three types of medications together may cause a small increase in serum potassium, more pronounced in diabetic women.

Food interactions

[CAUTION] Caution is advised when consuming alcohol with Drospirenone + Estradiol. Please consult your doctor.

Use in pregnancy

[UNSAFE] Drospirenone + Estradiol is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Use in lactation

[CONSULT YOUR DOCTOR] Drospirenone + Estradiol is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Nonhormonal and progestin-only contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum

Renal / hepatic impairment

[UNSAFE] Drospirenone + Estradiol is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. [UNSAFE] Drospirenone + Estradiol is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Common questions

Need to know about contraceptive pills and their doses if I am having Pcods issues. take dronis 30 once daily for 21 days for 6 cycles for now. starti g from day 1 of ur cycle each month. exercise daily HI. I HAVE A PROBLEM OF PCOS SINCE 1 YEAR, MY GYNEC SUGGESTED ME TO TAKE DRONIS 20 FOR THIS. IS IT GOOD FOR PCOS OR NOT ? AND PLEASE TELL ME THE THE SIDE EFFECTS OF DRONIS 20. It is oral contraceptive pill it will make periods regular but is no cure for pco I am taking dronis 30 regularly.but on tuesday i missed one and i take only one wednesday.what should i do. Should i take 2 on thrusday. Is thr any problem. Pls suggest Yes take 2 pills the next day and continue as usual I am taking DRONIS 30 as my prescribe it. but now I am feeling weakness and my eye color change to light yellow is it the side effect of this medicine or I have to go for my health check up? You should go for liver function test. This could be the side effect of this med. My current given me advice to tke dronis 30 but After taking medicine i am not feeling comfortable after 30 -40 min start vomiting sensation and waterly coming in my mouth please suggest any other treatment excet opration for overian cyst Its too uncomfortable for me to continue with this tablet with addition m taking pan 40 also but discomfort is same i am Also want to conceive Ok don't take it wait for period and get an ultrasound repeated Which tablet do women have to avoid pregnency? In how many hours shoud it be consumed You can take emergency contraception with in 72 hours After abortion for precaution what I can take condom or choice tablet Its best to take regular pills like choice of Loette for contraception. I was married in 2015 may. I have been using dronis 30 since then! Now that we are planning to have kids, I have discontinued them since december. As we stay abroad and have no proper guidance, please help me with the supplements i need (if any) for both my health and conceiving! I have no medical problems so far and no allergies and not overweight too! Start taking folvite 5 mg once daily. That's all you need

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.