Rythmosin150mg
Rx- Generic:
- Propafenone Hydrochloride
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 15/unit
Pack: ৳ 150
At a glance
Propafenone Hydrochloride — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Propafenone Hydrochloride is a medicine used to treat arrhythmia (abnormal heart rhythm). It restores normal heart rhythm by blocking abnormal electrical signals in the heart. This helps to maintain a regular and steady heartbeat. Propafenone Hydrochloride should be taken regularly as advised by the doctor. You should take it with food and at a fixed time. This medicine should not be stopped abruptly without consulting the doctor as this can worsen your condition. Regular follow-up with your doctor is advised while using this medicine. It may cause side effects like dizziness, headache, blurred vision, nausea, constipation and fatigue in some patients. Your doctor may advise for regular monitoring of kidney function while you are taking this medicine. This medicine may not be suitable for some people. You must inform doctor if you are suffering from any liver or kidney disease. Also let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it. Propafenone Hydrochloride is an anti-arrhythmic medication. It works by blocking abnormal electrical signals in the heart to correct irregular heartbeat to a normal rhythm.
Indications
• Arrhythmia
Mechanism of action
Propafenone is a class 1C antiarrhythmic drug with local anaesthetic effects, and a direct stabilising action on myocardial membranes. The electrophysiological effect manifests itself in a reduction of upstroke velocity (Phase 0) of the monophasic action potential. In Purkinje fibers, and to a lesser extent myocardial fibers, propafenone reduces the fast inward current carried by sodium ions. Diastolic excitability threshold is increased and effective refractory period prolonged. Propafenone reduces spontaneous automaticity and depresses triggered activity.
Dosage
Adult Dose: Oral Supraventricular and ventricular arrhythmias, Atrial Fibrillation/Flutter Adult: For immediate-release tablet: Usual initial doses: 150 mg tid, may increase at intervals of 3-4 days up to 300 mg tid. Dose reduction is recommended in patients weighing <70 kg. Elderly: Dose reduction is recommended. Hepatic impairment: Dose reduction is recommended. Child Dose: Safety and efficacy not established
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Propafenone Hydrochloride is to be taken with food.
Missed dose
If you miss a dose of Propafenone Hydrochloride, skip it and continue with your normal schedule. Do not double the dose.
Side effects
Common: • Abdominal pain • Anxiety • Blurred vision • Breathlessness • Chest pain • Constipation • Dizziness • Dryness in mouth • Fatigue • Fever • Headache • Increased liver enzymes • Palpitations • Sleep disorder • Taste change • Visual impairment • Vomiting • Weakness
Precautions & warnings
[UNSAFE] Propafenone Hydrochloride may cause side effects which could affect your ability to drive. As Propafenone Hydrochloride may cause tiredness, dizziness, blurred vision and low blood pressure in some patients and this may affect your ability to drive. It may cause dizziness. Do not drive or perform activities require mental focus until you know how it affects you. Do not start any medicine including prescription or over-the-counter medicines without informing your doctor, as they may alter Propafenone Hydrochloride levels in your body. Your doctor may get blood tests done to check your sodium and potassium levels, kidney function, and lung function before starting treatment with this medicine. Your doctor may regularly monitor blood sugar level while taking this medicine. Inform your doctor if you experience slow or fast heart rate, chest pain, shortness of breath. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Do not stop taking medication suddenly without talking to your doctor.
Contraindications
Uncontrolled heart failure, marked hypotension, severe bradycardia and heart block, conduction abnormalities, cardiogenic shock, myasthenia gravis.
Drug interactions
Effect may be potentiated by local anesth, beta-blockers, TCA. May increase plasma level of propranolol, metoprolol, desipramine, cyclosporin, digoxin, theophylline. Plasma conc may rise when taken simultaneously w/ cimetidine or quinidine. May enhance effect of anticoagulant. Simultaneous administration w/ phenobarb or rifamycin may decrease propafenone plasma conc, possibly in sub-therapeutic levels.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Propafenone Hydrochloride. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Propafenone Hydrochloride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Propafenone Hydrochloride is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Propafenone Hydrochloride is safe to use in patients with kidney disease. No dose adjustment of Propafenone Hydrochloride is recommended. However, talk to your doctor if you have any underlying kidney disease. [CAUTION] Propafenone Hydrochloride should be used with caution in patients with liver disease. Dose adjustment of Propafenone Hydrochloride may be needed. Please consult your doctor.
Common questions
Having severe acidity in stomach Take Tablet Rantac 150 twice a day Having difficulty in getting full erections. I take concor 1.25 and roseday 10 as prescribed for arrhythmia. What can be prescribed to me ? Treatment for erectile dysfunction: 1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects I am dybitic but sugar under control ihave a white discharge vagina sice last four dsys discharge is very thick ihave to change my undegsrments frequently kindly advise Take fluconazole 150 mg tablet and apply clotrimazole ointment I have got some white spots on my neck , shoulder and back which is like fungul infection.this is due to some skin infection or due to sweat.kindly suggest me some remedy to cure it as soon as possible as it is spreading on my chest also. Take Tab.Fluconazole 150 only one tablet after meal,apply Clotrin ointment Badsool,itching problem in sitting area Take Tab.Fluconazole 150 only one tablet after meal,apply Clotrin ointment The ecg report is Sinus Arrhythmia and short PR interval. What does it mean? Normal for d age The ecg report is Sinus Arrhythmia and Short PR interval. What does it mean? What does it mean? Normal for 5 yrs I am suffering from Dandruff and hairfall take fluconazole 150 mg1 tablet every week for 4 weeksand use shampoo Ketomac twice weekly