৳ 13/unit
Pack: ৳ 13
৳ 13/unit
Pack: ৳ 13
At a glance
Chlorpheniramine Maleate is an antiallergic medication used in the treatment of various allergic conditions including urticaria, vasomotor rhinitis, cough, common cold, and motion sickness.
Indications
- Urticaria
- Sensitivity reactions
- Angioneurotic edema
- Vasomotor rhinitis
- Cough
- Common cold
- Motion sickness
- Other allergic conditions
Pharmacology
Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Chlorpheniramine Maleate exerts its effects by blocking H1-receptor competitively.
Dosage
Adult Dose (Oral): 4 mg every 4-6 hours, maximum 24 mg daily.
Adult Dose (Parenteral): Emergency treatment of anaphylactic shock: 10-20 mg IM, SC, or slow IV (over 1 min), max 40 mg/day.
Pediatric Dose (Oral):
| Age | Dose | Schedule | Max |
|---|---|---|---|
| 1-2 years | 1 mg | Twice daily | — |
| 2-5 years | 1 mg | Every 4-6 hours | 6 mg/day |
| 6-12 years | 2 mg | Every 4-6 hours | 12 mg/day |
Pediatric Dose (Parenteral): 87.5 mcg/kg SC 4 times daily.
Side effects
Common Side Effects:
- Dry mouth
- Sleepiness
- Drowsiness
- Loss of appetite
- Nausea
- Dizziness
- Muscular weakness
- Gastrointestinal upset
Use in pregnancy
[SAFE IF PRESCRIBED] Chlorpheniramine Maleate is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Pregnancy Category B. Avoid use during the first trimester of pregnancy.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- [UNSAFE] Chlorpheniramine Maleate may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
- Avoid driving or operating dangerous machinery as it may decrease alertness.
- Avoid consuming alcohol as it may cause excessive sleepiness or drowsiness.
- Use with caution in patients with glaucoma and prostatic hypertrophy.
- Avoid during the first trimester of pregnancy.
Overdose effects
Overdose symptoms: CNS depression (sedation, apnea, CV collapse), CNS stimulation (insomnia, hallucinations, tremors, convulsions), tinnitus, blurred vision, dizziness, ataxia, hypotension. Stimulation and atropine-like signs (dry mouth, fixed dilated pupils, flushing, hyperthermia, GI symptoms) are more likely in children.
Storage conditions
Store in a cool (below 25°C) and dry place protected from light. Keep out of the reach of children.