৳ 10/unit
Pack: ৳ 10
৳ 10/unit
Pack: ৳ 10
At a glance
Dipyridamole is an antiplatelet medication used for stroke prevention and prevention of blood clotting after heart valve replacement.
Indications
- Secondary prevention of ischaemic stroke and transient ischaemic attacks
- Prophylaxis of thromboembolism associated with prosthetic heart valves
Pharmacology
Dipyridamole causes an accumulation of adenosine, adenine nucleotides and cAMP by inhibiting the activity of adenosine deaminase and phosphodiesterase thus inhibiting platelet aggregation and may cause vasodilation.
Dosage
Adult: 75-100 mg every 6 hours (as adjunct to warfarin).
Child: 3-6 mg/kg/day divided every 6-8 hours.
Side effects
Common: Headache, flushing, dizziness, nausea, diarrhea, decreased blood pressure.
Other: Thrombocytopenia, angioedema, angina pectoris, tachycardia, hypotension, bronchospasm, rash, urticaria, myalgia, post-procedural hemorrhage.
Use in pregnancy
Generally considered safe during pregnancy (animal studies show low or no adverse effects; limited human studies).
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
May affect driving ability (drowsiness, dizziness). Increased bleeding risk; be careful while shaving, cutting nails, or using sharp objects. May need to temporarily stop before surgery or dental treatment. Caution in pregnancy and lactation.
Overdose effects
Overdose may cause feeling warm, flushes, sweating, accelerated pulse, restlessness, weakness, dizziness, drop in blood pressure, and anginal complaints.
Storage conditions
Keep below 30°C temperature, away from light & moisture.