৳ 1/unit
Pack: ৳ 100
৳ 1/unit
Pack: ৳ 100
At a glance
Terfenadine is an antihistamine used for allergic conditions. It relieves itching, swelling, and rashes by blocking histamine effects. Its use has been banned due to serious side effects.
Indications
- Allergic conditions
Pharmacology
Terfenadine is a non-sedating antihistamine that blocks peripheral H1 receptors to prevent histamine-induced allergic reactions. However, due to CYP3A4 metabolism, it has significant drug interaction and QT prolongation risks.
Dosage
Adult Dose (Oral):
- 60-120 mg/day in the morning or 60 mg twice daily
- Maximum: 120 mg/day
Pediatric Dose (>12 years, >50 kg):
- 60-120 mg/day in the morning or 60 mg twice daily
- Maximum: 120 mg/day
Side effects
Common Side Effects:
- Diarrhea, headache
- Elevated liver enzymes
- Joint pain, muscle pain
- Loss of appetite, nausea
- Rash, abdominal pain
Serious (Rare):
- QT interval prolongation
- Torsade de pointes (fatal arrhythmia)
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Banned in many countries due to serious side effects
- Stop use 3 days before allergy testing
- Caution in liver disease
- Caution in pregnancy and lactation
Overdose effects
Overdose may cause QT prolongation and arrhythmia risk; provide symptomatic treatment.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.