osudhkosh
New
Company•General Pharmaceuticals Ltd.

Setra 25

Rx
Generic: Sertraline Hydrochloride

৳ 4/unit

Pack: ৳ 40

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At a glance

Sertraline Hydrochloride is an SSRI antidepressant used for the treatment of major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder.

Indications
  • Major Depressive Disorder (MDD)
  • Obsessive-Compulsive Disorder (OCD)
  • Panic Disorder (PD)
  • Post-Traumatic Stress Disorder (PTSD)
  • Social Anxiety Disorder (SAD)
  • Premenstrual Dysphoric Disorder (PMDD)
Pharmacology

Sertraline inhibits CNS neuronal 5-HT reuptake, increasing serotonin concentration at synaptic clefts, which enhances sustained activity at postsynaptic receptor sites and improves depressive symptoms. Reduced serotonin turnover in the brain also contributes to its action.

Dosage

Adult Dose (Oral):

  • MDD/OCD: Start 50 mg/day; increase by 50 mg weekly; max 200 mg/day
  • PD/PTSD/SAD: Start 25 mg/day for 1 week; then 50 mg/day; increase by 50 mg weekly; max 200 mg/day
  • PMDD (Continuous): Start 50 mg/day; increase by 50 mg per cycle; max 150 mg/day
  • PMDD (Intermittent): Start 50 mg/day (luteal phase); increase by 50 mg per cycle; max 100 mg/day

Pediatric Dose (Oral) – OCD:

  • 6-12 years: Start 25 mg/day
  • 13-17 years: Start 50 mg/day
  • Max 200 mg/day
Side effects

Common Side Effects:

  • Nausea, diarrhea, loss of appetite
  • Insomnia, tremor, increased sweating
  • Delayed ejaculation, erectile dysfunction
  • Decreased sexual desire
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Monitor for suicidal thoughts/behavior (especially at 2-3 weeks)
  • Do not use with or within 14 days of MAOIs
  • Reduce dose in liver disease; avoid in severe liver disease
  • Caution in pregnancy and lactation
  • May affect driving ability
Overdose effects

Overdose may cause serotonin syndrome; hemodialysis not effective; provide symptomatic treatment.

Storage conditions

Store below 30°C; keep out of reach of children.

Sertraline Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.