৳ 70.21/unit
Pack: ৳ 70.21
৳ 70.21/unit
Pack: ৳ 70.21
At a glance
Acyclovir (Ophthalmic) is an antiviral eye ointment used for the treatment of herpes simplex keratitis (eye infection caused by herpes simplex virus). It stops viral multiplication on the cornea and clears the infection.
Indications
Herpes simplex keratitis.
Pharmacology
Acyclovir is highly active in vitro against Herpes simplex (HSV) types I and II and Varicella zoster viruses, with low toxicity to mammalian cells. Acyclovir is phosphorylated to the active compound acyclovir triphosphate after entry into herpes infected cells. The first step requires viral-coded thymidine kinase. Acyclovir triphosphate acts as an inhibitor and substrate for herpes-specific DNA polymerase, preventing viral DNA synthesis without affecting normal cellular processes.
Dosage
Same dosage for all ages:
- Place a 10 mm ribbon of ointment inside the lower conjunctival sac
- Apply 5 times daily (approximately every 4 hours)
- Continue treatment for at least 3 days after healing is complete
Side effects
Very common (>10%): Superficial punctate keratopathy (does not require treatment termination and heals without sequelae)
Common (1-10%): Transient mild stinging of the eye immediately following application, conjunctivitis
Rare (<1%): Blepharitis
Use in pregnancy
Pregnancy Category: B. No adequate controlled studies in pregnant women. It is not known whether topically applied acyclovir is excreted in breast milk. Use only if clearly needed with medical advice.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not exceed the recommended dosage, frequency, or duration of treatment
- Continue treatment for at least 3 days after healing is complete
- Do not wear contact lenses during treatment
- Do not contaminate the tube tip (do not touch the tip to the eye or any surface)
- Do not apply at nighttime
- Discard the tube one month after opening
Overdose effects
No adverse effects would be expected if the entire tube containing 90 mg acyclovir were ingested orally.
Storage conditions
Store in a cool and dry place, protected from light. Keep out of reach of children. Do not touch the tube tip. Discard one month after opening.